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Número de registros en este nivel: 22.

A

Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Cerrado Inglés Diets enriched in plant-based foods are associated with the maintenance of a good well-being and with the prevention of many non-communicable diseases. The health effects of fruits and vegetables consumption are mainly due to the presence of micronutrients, including vitamins and minerals, and polyphenols, plant secondary metabolites. One of the most important classes of phenolic compounds are anthocyanins, that confer the typical purple-red color to many foods, such as berries, peaches, plums, red onions, purple corn, eggplants, as well as purple carrots, sweet potatoes and red cabbages, among others. This commentary aims to briefly highlight the progress made by science in the last years, focusing on some unexpected aspects related with anthocyanins, such as their bioavailability, their health effects and their relationship with gut microbiota metadata Giampieri, Francesca; Cianciosi, Danila; Alvarez-Suarez, José M.; Quiles, José L.; Forbes-Hernández, Tamara Y.; Navarro-Hortal, María D.; Machì, Michele; Pali-Casanova, Ramón; Martínez Espinosa, Julio César; Chen, Xiumin; Zhang, Di; Bai, Weibin; Lingmin, Tian; Mezzetti, Bruno; Battino, Maurizio y Diaz, Yasmany Armas mail francesca.giampieri@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, jose.quiles@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, ramon.pali@unini.edu.mx, ulio.martinez@unini.edu.mx, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, maurizio.battino@uneatlantico.es, SIN ESPECIFICAR (2023) Anthocyanins: what do we know until now? Journal of Berry Research. pp. 1-6. ISSN 18785093

Tesis Materias > Alimentación
Materias > Educación física y el deporte
Materias > Psicología
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Tesis Doctorales Cerrado Español La Actividad Física (AF) es muy importante en la edad escolar por ser precursora de hábitos saludables en la vida adulta. Asociada a numerosos beneficios sobre la salud y a la reducción de enfermedades no transmisibles. A nivel psicológico se la asocia con un menor nivel de ansiedad y mejor autoconfianza. Además, la AF se relaciona con la alimentación, donde la Dieta Mediterránea (DM) es esencial para tener un estilo de vida saludable. La investigación consta de dos estudios descriptivo-transversales, que analizarán variables relacionadas con la AF, la salud y los estados de ánimo. La muestra ha estado compuesta por 485 escolares de Infantil, Primaria y Secundaria: •Estudio 1: Se han descrito los niveles y diferencias encontradas con rela-ción al deporte practicado. A su vez, se midieron las siguientes variables: el Índice Cintura Cadera (ICC), Índice Cintura Muslo (ICM), Índice de Masa Corporal (IMC), y porcentaje de grasa corporal; los deportistas auto informaron respecto al volumen de actividad física practicada (VAFP) mediante un cuestionario Sociodemográfico, y la Adherencia a la Dieta Mediterránea (ADM) con el Índice de calidad de la Dieta Mediterránea (KIDMED). La aptitud cardiorrespiratoria (AC) mediante el test de Course Navette. •Estudio 2: Se han descrito y comparado los estados de ánimo, utilizando un cuestionario de autovaloración psicológica (POMS) en relación al deporte practicado y respecto a si son deportistas federados o escolares. En ambos estudios se analizaron tres deportes: atletismo, fútbol y hockey hierba. En los resultados se ha encontrado una asociación positiva entre la práctica de deporte federado y las variables analizadas. Es decir, que realizar dicha práctica es sinónimo de salud, en lo que se refiere a mejores valores en variables relacionadas con la condición física, la alimentación o perfil de estado de ánimo. metadata Fernández García, Javier mail javier.fernandez@doctorado.unib.org (2022) Aspectos antropométricos, físicos, nutricionales y psicológicos en deportistas federados y escolares. Doctoral thesis, Universidad Internacional Iberoamericana Puerto Rico.

Tesis Materias > Alimentación
Materias > Ciencias Sociales
Universidad Internacional Iberoamericana Puerto Rico > Docencia > Trabajos finales de Máster Cerrado Portugués O tema deste estudo está pautado em um estudo de caso na avaliação da utilização do pivô central na irrigação do cultivo do arroz no município de Uruguaiana-RS. Para entender o problema principal do estudo que é a falta e ou dificuldade de irrigação do cultivo de arroz onde existe escassez de água, pretendendo estudar a utilização do pivô central e sua efetividade nos cultivos. Nos últimos anos estamos percebendo com maior intensidade que a escassez de água tem prejudicado diversas regiões de nosso País na irrigação das plantações que demandam de maior irrigação como o cultivo do arroz quando existe uma maior necessidade de demanda de água para sua irrigação. Este trabalho teve por objetivo geral avaliar a utilização do pivô central na irrigação do cultivo de arroz. E como objetivos específicos: analisar as questões econômicas, na relação investimento, lucro e prejuízo com o uso do pivô central, analisar os fatores ambientais, considerando, tanto o modo de instalação e funcionamento do equipamento, analisar se há o uso racional e responsável dos recursos hídricos. A metodologia utilizada foi de pesquisa bibliográfica e estudo de caso de observação de funcionamento do sistema de pivô central de irrigação. E como resultado percebe-se que este sistema quando em bom funcionamento pode colaborar significativamente na economia de energia elétrica, considerando um retorno importante para novos investimentos em sistemas de irrigação e obteve-se como conclusão principal que a utilização do pivô central se mostra como um grande potencial de economia e rentabilidade nos cultivos de arroz, podendo apresentar também um retorno do capital investido. metadata dos Santos Campão, Guilherme mail guicampao@gmail.com (2022) Avaliação da utilização de pivô central na irrigação do cultivo do arroz no município de Uruguaiana-RS: um estudo de caso. Masters thesis, Universidad Internacional Iberoamericana Puerto Rico.

B

Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Cerrado Inglés Betalains are water-soluble, nitrogen-containing vacuolar pigment and can be divided into two subclasses: the yellow – orange betaxanthins and the red – violet betacyanin. These pigments can be found mainly in Latin America, but also in some parts of Asia, Africa, Australia and in the Mediterranean area. In this work an overview related with the status of research about betalains extracted from Opuntia spp and the enforces made to evaluate their positive incidence in the human body is provided. Several studies enhance their anticancer, anti-inflammatory and antioxidant properties. They also exhibit antimicrobial and antidiabetic effect. Taking into account these properties, betalains seem to be a promising natural alternative as a colorant to replace the synthetic ones in the food additive industry. In addition, the use of Opuntia spp fruits as possible colorant sources in the Food Industry, may contribute positively to the sustainable development in semi-arid regions. metadata Armas Diaz, Yasmany; Qi, Zexiu; Yang, Bei; Martínez López, Nohora Milena; Briones Urbano, Mercedes y Cianciosi, Danila mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, nohora.martinez@uneatlantico.es, mercedes.briones@uneatlantico.es, SIN ESPECIFICAR (2023) Betalains: The main bioactive compounds of Opuntia spp and their possible health benefits in the Mediterranean diet. Mediterranean Journal of Nutrition and Metabolism, 16 (3). pp. 181-190. ISSN 1973798X

C

Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Abierto Inglés Alpha-linolenic acid (ALA) is a long-chain polyunsaturated essential fatty acid of the Ω3 series found mainly in vegetables, especially in the fatty part of oilseeds, dried fruit, berries, and legumes. It is very popular for its preventive use in several diseases: It seems to reduce the risk of the onset or decrease some phenomena related to inflammation, oxidative stress, and conditions of dysregulation of the immune response. Recent studies have confirmed these unhealthy situations also in patients with severe coronavirus disease 2019 (COVID-19). Different findings (in vitro, in vivo, and clinical ones), summarized and analyzed in this review, have showed an important role of ALA in other various non-COVID physiological and pathological situations against “cytokines storm,” chemokines secretion, oxidative stress, and dysregulation of immune cells that are also involved in the infection of the 2019 novel coronavirus. According to the effects of ALA against all the aforementioned situations (also present in patients with a severe clinical picture of severe acute respiratory syndrome-(CoV-2) infection), there may be the biologic plausibility of a prophylactic effect of this compound against COVID-19 symptoms and fatality. metadata Cianciosi, Danila; Diaz, Yasmany Armas; Gaddi, Antonio Vittorino; Capello, Fabio; Savo, Maria Teresa; Pali-Casanova, Ramón; Martínez Espinosa, Julio César; Pascual Barrera, Alina Eugenia; Navarro‐Hortal, Maria‐Dolores; Tian, Lingmin; Bai, Weibin; Giampieri, Francesca y Battino, Maurizio mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, ramon.pali@unini.edu.mx, ulio.martinez@unini.edu.mx, alina.pascual@unini.edu.mx, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, francesca.giampieri@uneatlantico.es, SIN ESPECIFICAR (2023) Can alpha‐linolenic acid be a modulator of “cytokine storm,” oxidative stress and immune response in SARS‐CoV‐2 infection? Food Frontiers. ISSN 2643-8429

Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Cerrado Inglés Manuka honey, which is rich in pinocembrin, quercetin, naringenin, salicylic, p-coumaric, ferulic, syringic and 3,4-dihydroxybenzoic acids, has been shown to have pleiotropic effects against colon cancer cells. In this study, potential chemosensitizing effects of Manuka honey against 5-Fluorouracil were investigated in colonspheres enriched with cancer stem cells (CSCs), which are responsible for chemoresistance. Results showed that 5-Fluorouracil increased when it was combined with Manuka honey by downregulating the gene expression of both ATP-binding cassette sub-family G member 2, an efflux pump and thymidylate synthase, the main target of 5-Fluorouracil which regulates the ex novo DNA synthesis. Manuka honey was associated with decreased self-renewal ability by CSCs, regulating expression of several genes in Wnt/β-catenin, Hedgehog and Notch pathways. This preliminary study opens new areas of research into the effects of natural compounds in combination with pharmaceuticals and, potentially, increase efficacy or reduce adverse effects. metadata Cianciosi, Danila; Armas Diaz, Yasmany; Alvarez-Suarez, José M.; Chen, Xiumin; Zhang, Di; Martínez López, Nohora Milena; Briones Urbano, Mercedes; Quiles, José L.; Amici, Adolfo; Battino, Maurizio y Giampieri, Francesca mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, nohora.martinez@uneatlantico.es, mercedes.briones@uneatlantico.es, jose.quiles@uneatlantico.es, SIN ESPECIFICAR, maurizio.battino@uneatlantico.es, francesca.giampieri@uneatlantico.es (2023) Can the phenolic compounds of Manuka honey chemosensitize colon cancer stem cells? A deep insight into the effect on chemoresistance and self-renewal. Food Chemistry, 427. p. 136684. ISSN 03088146

D

Tesis Materias > Ingeniería
Materias > Alimentación
Materias > Ciencias Sociales
Universidad Internacional Iberoamericana México > Docencia > Trabajos finales de Máster
Universidad Internacional Iberoamericana Puerto Rico > Docencia > Trabajos finales de Máster
Cerrado Español La identificación de desperdicios de producción o actividades que afectan a los procesos de producción, con la finalidad de reducirlos o eliminarlos, es un esfuerzo que las organizaciones, de todo tipo, realizan para mejorar su sistema de producción, incrementar su rentabilidad y productividad, y además reducir costos. En este sentido y con base en lo expuesto, en este proyecto de investigación de diseño no experimental, con un enfoque cualitativo y cuantitativo, de tipo documental, descriptivo y evaluativo, se realizará un trabajo de observación en el lugar de los hechos con el fin de identificar los desperdicios de producción (sobreproducción, movimiento, espera, transporte, sobre proceso, stock o inventario, defectos) presentes en el proceso de preparación de canastas agroecológicas del Centro de Acopio de Productos Agropecuarios de la Compañía de Economía Mixta AGROAZUAY GPA, en la ciudad de Cuenca, Ecuador, así como, describir las características que acompañan a estos desperdicios, y a partir de esto, analizar los efectos de los desperdicios identificados en el proceso de estudio. Una vez situados en este punto y como parte complementaria de la investigación, se diseñará una propuesta para reducir estos desperdicios de producción que se encuentran presentes en el proceso sobre el cual se investiga. metadata Rea Parra, Pablo Humberto mail pablorhea@hotmail.com (2022) Desperdicios de producción en el proceso de preparación de canastas agroecológicas del centro de acopio de productos agropecuarios de la compañía de economía mixta AGROAZUAY GPA, en la ciudad de Cuenca, Ecuador. Masters thesis, SIN ESPECIFICAR.

Artículo Materias > Alimentación Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica Abierto Español En la presente investigación, se evaluó la presencia de E. coli, hongos y levaduras en la harina proveniente de las cascarillas de las variedades de cacao Nacional Arriba y el cacao CCN51 en Ecuador, para su uso en los procesos de elaboración de galletas, panes y pasteles. Se tomaron cinco muestras de 2000 g cada una, de 5 lotes diferentes para cada variedad de cacao en dos industrias cacaoteras en la provincia del Guayas. Se realizó la molienda con un molino marca Oster, se homogenizaron las muestras y se empacaron 500 g de las cáscaras molidas de cada variedad en fundas de polietileno de baja densidad, para poder realizar los análisis microbiológicos. Las muestras fueron enviadas a un laboratorio certificado para realizar los análisis correspondientes. Debido a que no existe alguna norma de calidad para la harina proveniente de cascarillas de cacao en Ecuador, se aplicaron las normas INEN 616 e INEN 621, las cuales definen los requisitos que debe cumplir la harina de trigo y los chocolates respetivamente para que sea apta para el consumo humano, comprobando que la harina proveniente de las cascarillas de ambas variedades cumple con los criterios establecidos en estas normas. metadata El Salous, Ahmed y Pascual Barrera, Alina Eugenia mail SIN ESPECIFICAR, alina.pascual@unini.edu.mx (2018) Determinación de e. Coli, hongos y levaduras en la harina proveniente de las cascarillas de dos variedades de cacao en Ecuador. Revista Universidad y Sociedad, 10 (1). pp. 164-167.

E

Artículo Materias > Alimentación Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica Abierto Inglés University students frequently develop unhealthy eating habits. However, it is unknown if students enrolled in academic programs related to nutrition and culinary arts have healthier eating habits. We evaluated the relationship of eating habits and nutritional status of students in academic programs with knowledge on nutrition, as well as cooking methods and techniques. A descriptive cross-sectional study was conducted in spring of 2019, while we completed a survey measuring eating habits and knowledge on nutrition, as well as cooking methods and techniques. Anthropometric measurements were collected for nutritional status estimation. The non-probabilistic convenience sample comprised 93 students pursuing degrees at Universidad Ana G. Mendez, Puerto Rico. Inadequate body mass index (BMI) was observed in 59% of the students. Eating habits, knowledge on nutrition, and knowledge on cooking methods and techniques were inadequate in 86%, 68%, and 41% of the population, respectively. Eating habits were associated with knowledge on nutrition and academic program, but not with knowledge on cooking methods and techniques. Most students reported having inadequate eating habits and BMI. Nutrition and dietetics students had the best knowledge on nutrition compared to culinary management students, a majority of whom had inadequate knowledge. We can conclude that there are other factors inherent to students’ life that may have a stronger influence on eating habits metadata Rivera Medina, Christian; Briones Urbano, Mercedes; de Jesús Espinosa, Aixa y Toledo López, Ángel mail SIN ESPECIFICAR, mercedes.briones@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR (2020) Eating Habits Associated with Nutrition-Related Knowledge among University Students Enrolled in Academic Programs Related to Nutrition and Culinary Arts in Puerto Rico. Nutrients, 12 (5). p. 1408. ISSN 2072-6643

Tesis Materias > Ingeniería
Materias > Alimentación
Materias > Educación
Universidad Internacional Iberoamericana Puerto Rico > Docencia > Trabajos finales de Máster Cerrado Español Esta investigación se realizó en la provincia de Santo domingo de los Tsáchilas – Ecuador, en una granja avícola de 8 galpones de pollo de engorde con una capacidad de 320000 pollos. El objetivo principal fue la eliminación de los desechos industriales avícolas puesto que durante la crianza de pollos de engorde se utiliza papel periódico en la recepción de las aves desde su llegada hasta aproximadamente el segundo o tercer día de alojamiento en galpones, el uso de este papel es para suministrar y dar accesibilidad a los pollitos bebe al alimento logrando así desarrollar su potencial desde los primeros días de vida; a partir del segundo o tercer día el papel utilizado en la recepción se transforma en un desecho industrial ya que este se lo retira de los galpones para evitar empastamientos en las camas y posibles lesiones en las patas de las aves. La prueba se realizó comparando 8 galpones de producción de pollos de engorde de los cuales en 4 galpones se retiró el papel generando desechos y 4 galpones se procedió a incorporar el papel al material de cama eliminando los desechos industriales avícolas. Se analizaron variables como la cantidad de desechos generados, los costos que involucran en cada tratamiento y la generación de impacto ambiental a las cuales se realizó un análisis descriptivo debido al interés del tema; por otro lado, para las variables de ambiente, como mediciones de amoniaco y humedad, así como para los parámetros productivos o zootécnicos se realizó un análisis de varianza para medir medias de los tratamientos y observar si existen diferencias significativas. Se obtuvo varios beneficios con el aprovechamiento del papel al incorporarlo al material de cama, el principal no generar contaminación e impacto ambiental, no llenar espacios en vertederos lo cual a la par es un impacto social positivo ya que se dispondría de estos espacios para los desechos de la comunidad, por otro lado los avicultores ahorran en costos como transporte de desechos, pagos en vertederos o municipios, menor mano de obra por actividades como el retiro de papel y se demostró que la incorporación de papel al material de cama no afecta en los resultados zootécnicos o productivos de las aves. metadata Pazmiño Valencia, Edison Paúl mail paulsin_pv@hotmail.com (2022) Eliminación de los desechos industriales generados en la avicultura debido a la utilización de papel en la recepción de pollitos BB, mediante la incorporación al material de cama. Masters thesis, SIN ESPECIFICAR.

F

Artículo Materias > Biomedicina
Materias > Educación física y el deporte
Materias > Alimentación
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Abierto Español El presente estudio tiene como objetivo determinar las relaciones entre los valores de funcionalidad motriz, estado nutricional e índices antropométricos de salud en adolescentes chilenos de 12 a 15 años. Estudio de corte transversal con una muestra no probabilística y por conveniencia, con una muestra final de 384 escolares (13,04 ± 0,85 años). Todos los participantes asistieron a dos sesiones de evaluación, donde se les realizó un registro de la historia clínica y una examinación física médica. En la segunda sesión, se realizaron evaluaciones antropométricas y las pruebas consideradas en la batería Functional Movement Screen (FMS). Los resultados muestran un 46,62% de los adolescentes posee sobrepeso y/u obesidad. El score total de FMS fue de 14,29±2,85 y se encontraron diferencias significativas en el IMC (índice de masa corporal) p=0,000 y en el peso p=0,002 según dependencia administrativa. Existe una relación entre FMS y PC (Perímetro de cintura), IMC e ICE (índice cintura estatura) (r=-0,31**p<0,003, r=-0,14**p<0,004 y r=0,38**p<0,003 respectivamente). También se encontró que aquellos escolares que presentan riesgo cardio metabólico también ostentarían un mayor riesgo relacionado con una baja calidad de la funcionalidad motriz. Se concluye que los niveles elevados de parámetros antropométricos de riesgo cardiovascular en especial el exceso de peso y el elevado perímetro de cintura se relacionan con una deficiente funcionalidad motriz. Y por otra parte se generan problemáticas cardiovasculares en esta etapa de la vida sin mayor distinción de sexo y dependencia administraba de los colegios, lo cual hace ver que la mal nutrición y la falta de actividad física impacta de manera transversal a la sociedad. metadata Rodríguez Canales, Carolina; Hinojosa Torres, Claudio; Merellano-Navarro, Eugenio; Barraza-Gómez, Fernando y Hecht-Chau, Gernot mail carolina.rodriguez@unini.org, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR (2022) Funcionalidad motriz, estado nutricional e índices antropométricos de riesgo cardiometabólico en adolescentes chilenos de 12 a 15 años. Retos: nuevas tendencias en educación f\'\isica, deporte y recreación (45). pp. 400-409.

H

Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Abierto Inglés Much of nutrition research has been conventionally based on the use of simplistic in vitro systems or animal models, which have been extensively employed in an effort to better understand the relationships between diet and complex diseases as well as to evaluate food safety. Although these models have undeniably contributed to increase our mechanistic understanding of basic biological processes, they do not adequately model complex human physiopathological phenomena, creating concerns about the translatability to humans. During the last decade, extraordinary advancement in stem cell culturing, three-dimensional cell cultures, sequencing technologies, and computer science has occurred, which has originated a wealth of novel human-based and more physiologically relevant tools. These tools, also known as “new approach methodologies,” which comprise patient-derived organoids, organs-on-chip, multi-omics approach, along with computational models and analysis, represent innovative and exciting tools to forward nutrition research from a human-biology-oriented perspective. After considering some shortcomings of conventional in vitro and vivo approaches, here we describe the main novel available and emerging tools that are appropriate for designing a more human-relevant nutrition research. Our aim is to encourage discussion on the opportunity to explore innovative paths in nutrition research and to promote a paradigm-change toward a more human biology-focused approach to better understand human nutritional pathophysiology, to evaluate novel food products, and to develop more effective targeted preventive or therapeutic strategies while helping in reducing the number and replacing animals employed in nutrition research. metadata Cassotta, Manuela; Cianciosi, Danila; Elexpuru Zabaleta, Maria; Elío Pascual, Iñaki; Sumalla Cano, Sandra; Giampieri, Francesca y Battino, Maurizio mail manucassotta@gmail.com, SIN ESPECIFICAR, maria.elexpuru@uneatlantico.es, inaki.elio@uneatlantico.es, sandra.sumalla@uneatlantico.es, francesca.giampieri@uneatlantico.es, maurizio.battino@uneatlantico.es (2024) Human‐based new approach methodologies to accelerate advances in nutrition research. Food Frontiers. pp. 1-32. ISSN 2643-8429

I

Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Abierto Inglés There is growing evidence that Alzheimer’s disease (AD) can be prevented by reducing risk factors involved in its pathophysiology. Food-derived bioactive molecules can help in the prevention and reduction of the progression of AD. Honey, a good source of antioxidants and bioactive molecules, has been tied to many health benefits, including those from neurological origin. Monofloral avocado honey (AH) has recently been characterized but its biomedical properties are still unknown. The aim of this study is to further its characterization, focusing on the phenolic profile. Moreover, its antioxidant capacity was assayed both in vitro and in vivo. Finally, a deep analysis on the pathophysiological features of AD such as oxidative stress, amyloid-β aggregation, and protein-tau-induced neurotoxicity were evaluated by using the experimental model C. elegans. AH exerted a high antioxidant capacity in vitro and in vivo. No toxicity was found in C. elegans at the dosages used. AH prevented ROS accumulation under AAPH-induced oxidative stress. Additionally, AH exerted a great anti-amyloidogenic capacity, which is relevant from the point of view of AD prevention. AH exacerbated the locomotive impairment in a C. elegans model of tauopathy, although the real contribution of AH remains unclear. The mechanisms under the observed effects might be attributed to an upregulation of daf-16 as well as to a strong ROS scavenging activity. These results increase the interest to study the biomedical applications of AH; however, more research is needed to deepen the mechanisms under the observed effects metadata Romero-Márquez, Jose M.; Navarro-Hortal, María D.; Orantes, Francisco J.; Esteban-Muñoz, Adelaida; Mazas Pérez-Oleaga, Cristina; Battino, Maurizio; Sánchez-González, Cristina; Rivas-García, Lorenzo; Giampieri, Francesca; Quiles, José L. y Forbes-Hernandez, Tamara Y. mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, cristina.mazas@uneatlantico.es, maurizio.battino@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, francesca.giampieri@uneatlantico.es, jose.quiles@uneatlantico.es, tamara.forbes@unini.edu.mx (2023) In Vivo Anti-Alzheimer and Antioxidant Properties of Avocado (Persea americana Mill.) Honey from Southern Spain. Antioxidants, 12 (2). p. 404. ISSN 2076-3921

Artículo Materias > Biomedicina
Materias > Alimentación
Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica
Abierto Inglés Isoflavones are a group of (poly)phenols, also defined as phytoestrogens, with chemical structures comparable with estrogen, that exert weak estrogenic effects. These phytochemical compounds have been targeted for their proven antioxidant and protective effects. Recognizing the increasing prevalence of cardiovascular diseases (CVD), there is a growing interest in understanding the potential cardiovascular benefits associated with these phytochemical compounds. Gut microbiota may play a key role in mediating the effects of isoflavones on vascular and endothelial functions, as it is directly implicated in isoflavones metabolism. The findings from randomized clinical trials indicate that isoflavone supplementation may exert putative effects on vascular biomarkers among healthy individuals, but not among patients affected by cardiometabolic disorders. These results might be explained by the enzymatic transformation to which isoflavones are subjected by the gut microbiota, suggesting that a diverse composition of the microbiota may determine the diverse bioavailability of these compounds. Specifically, the conversion of isoflavones in equol—a microbiota-derived metabolite—seems to differ between individuals. Further studies are needed to clarify the intricate molecular mechanisms behind these contrasting results. metadata Laudani, Samuele; Godos, Justyna; Romano, Giovanni Luca; Gozzo, Lucia; Di Domenico, Federica Martina; Dominguez Azpíroz, Irma; Martínez Díaz, Raquel; Giampieri, Francesca; Quiles, José L.; Battino, Maurizio; Drago, Filippo; Galvano, Fabio y Grosso, Giuseppe mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, irma.dominguez@unini.edu.mx, raquel.martinez@uneatlantico.es, francesca.giampieri@uneatlantico.es, jose.quiles@uneatlantico.es, maurizio.battino@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR (2024) Isoflavones Effects on Vascular and Endothelial Outcomes: How Is the Gut Microbiota Involved? Pharmaceuticals, 17 (2). p. 236. ISSN 1424-8247

M

Revista Materias > Alimentación Universidad Europea del Atlántico > Investigación > Revistas Científicas
Universidad Internacional Iberoamericana México > Investigación > Revistas Científicas
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Revistas Científicas
Universidad Internacional do Cuanza > Investigación > Revistas Científicas
Fundación Universitaria Internacional de Colombia > Investigación > Revistas Científicas
Abierto Inglés La revista MLS Health and Nutrition Research nace como una publicación semestral con el objetivo de publicar artículos originales de investigación y de revisión tanto en áreas básicas como aplicadas y metodológicas que supongan una contribución científica al progreso de cualquier ámbito de la salud y nutrición como objetivo principal. Los artículos incluidos en esta revista se publican en español, portugués e inglés. La vocación internacional de esta revista promueve la difusión del conocimiento en sus diferentes áreas. metadata SIN ESPECIFICAR mail mls@devnull.funiber.org (2022) MLS Health and Nutrition Research. [Revista]

Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica
Abierto Inglés The prevalence of sleep disorders, characterized by issues with quality, timing, and sleep duration is increasing globally. Among modifiable risk factors, diet quality has been suggested to influence sleep features. The Mediterranean diet is considered a landmark dietary pattern in terms of quality and effects on human health. However, dietary habits characterized by this cultural heritage should also be considered in the context of overall lifestyle behaviors, including sleep habits. This study aimed to systematically revise the literature relating to adherence to the Mediterranean diet and sleep features in observational studies. The systematic review comprised 23 reports describing the relation between adherence to the Mediterranean diet and different sleep features, including sleep quality, sleep duration, daytime sleepiness, and insomnia symptoms. The majority of the included studies were conducted in the Mediterranean basin and reported a significant association between a higher adherence to the Mediterranean diet and a lower likelihood of having poor sleep quality, inadequate sleep duration, excessive daytime sleepiness or symptoms of insomnia. Interestingly, additional studies conducted outside the Mediterranean basin showed a relationship between the adoption of a Mediterranean-type diet and sleep quality, suggesting that biological mechanisms sustaining such an association may exist. In conclusion, current evidence suggests a relationship between adhering to the Mediterranean diet and overall sleep quality and different sleep parameters. The plausible bidirectional association should be further investigated to understand whether the promotion of a healthy diet could be used as a tool to improve sleep quality. metadata Godos, Justyna; Ferri, Raffaele; Lanza, Giuseppe; Caraci, Filippo; Rojas Vistorte, Angel Olider; Yélamos Torres, Vanessa; Grosso, Giuseppe y Castellano, Sabrina mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, angel.rojas@uneatlantico.es, vanessa.yelamos@funiber.org, SIN ESPECIFICAR, SIN ESPECIFICAR (2024) Mediterranean Diet and Sleep Features: A Systematic Review of Current Evidence. Nutrients, 16 (2). p. 282. ISSN 2072-6643

P

Artículo Materias > Biomedicina
Materias > Alimentación
Universidad Europea del Atlántico > Investigación > Producción Científica
Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Cerrado Inglés Cactus has been used in traditional folk medicine because of its role in treating a number of diseases and conditions. Prickly pear fruit is an excellent source of secondary metabolites (i.e., betalains, flavonoids, and ascorbic acid) with health-promoting properties against many common human diseases, including diabetes, hypertension, hypercholesterolemia, rheumatic pain, gastric mucosa diseases and asthma. In addition, prickly pears are potential candidates for the development of low-cost functional foods because they grow with low water requirements in arid regions of the world. This review describes the main bioactive compounds found in this fruit and shows the in vitro and some clinical studies about the fruit of most important cactus (Opuntia ficus-indica) and its relationship with some chronic diseases. Even though a lot of effort have been done to study the relationship between this fruit and the human health, more studies on Opuntia ficus-indica could help better understand its pharmacological mechanism of action to provide clear scientific evidence to explain its traditional uses, and to identify its therapeutic potential in other diseases. metadata Armas Diaz, Yasmany; Machì, Michele; Salinari, Alessia; Mazas Pérez-Oleaga, Cristina; Martínez López, Nohora Milena; Briones Urbano, Mercedes y Cianciosi, Danila mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, cristina.mazas@uneatlantico.es, nohora.martinez@uneatlantico.es, mercedes.briones@uneatlantico.es, SIN ESPECIFICAR (2022) Prickly pear fruits from "Opuntia ficus-indica" varieties as a source of potential bioactive compounds in the Mediterranean diet. Mediterranean Journal of Nutrition and Metabolism, 15 (4). pp. 581-592. ISSN 1973798X

Tesis Materias > Alimentación Universidad Europea del Atlántico > Docencia > Trabajos finales de Máster
Universidad Internacional Iberoamericana Puerto Rico > Docencia > Trabajos finales de Máster
Cerrado Español Programa de transferencia de embriones bovinos de especialidad cárnica, elaborados a partir de la técnica fertilización in-vitro para pequeños y medianos ganaderos del Departamento del Huila. Dentro la seguridad alimentaria, la proteína roja (carne), es una fuente esencial de la dieta humana; para llegar a ella, los sistemas ganaderos, como ocurre en el departamento del Huila, no están haciendo un manejo equilibrado en la explotación ganadera; que mayoritariamente es de doble propósito, y tan solo un 5% destinada a ceba; generando impactos negativos ambientales y bajos rendimientos en la productividad cárnica, al no utilizar razas especializadas para la producción de carne. Por eso, el objetivo principal de este trabajo consistió en diseñar un programa transferencia de embriones bovinos de especialidad cárnica, elaborados a partir de la técnica Fertilización In-vitro (FIV) para pequeños y medianos ganaderos en el departamento del Huila. Fue necesario reconocer los grupos poblaciones influyentes y dependientes de la actividad ganadera; las razas especializadas de ganado vacuno en la producción de carne, y las técnicas de reproducción bovina. La investigación fue documental tipo meta análisis con énfasis cualitativo descriptivo explicativo. En sus resultados se encontró: déficit de 10.78 kg/persona año, de suministro de carne; el 59% del ganado sacrificado, son hembras, pesan menos que el macho; baja productividad animal y rendimiento cárnico; ciclo ganadero largo entre 37 y 42 meses. Ante esa situación, se diseñó el programa FIVTEBEC-DSH Versión 1-2020, donde se establecieron unas fichas protocolarias para ser desarrolladas en cinco etapas: Selección y compromiso ganaderos de la región; procedimentales para la selección de bovinos; de obtención y clasificación de los embriones; de producción in vitro, y de la transferencia de embriones, empleándose razas especializadas de carne como: Brahman Rojo y Blanco, Simmental y Simbrah 5/8-3/8. metadata González González, Arlinson mail argoz2050@gmail.com (2020) Programa de Transferencia de Embriones Bovinos de Especialidad Cárnica, Elaborados a partir de la Técnica Fertilización In-Vitro para Pequeños y Medianos Ganaderos del Departamento del Huila. Masters thesis, SIN ESPECIFICAR.

R

Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Abierto Inglés It has been hypothesized that alterations in the composition of the gut microbiota might be associated with the onset of certain human pathologies, such as Alzheimer disease, a neurodegenerative syndrome associated with cerebral accumulation of amyloid-β fibrils. It has been shown that bacteria populating the gut microbiota can release significant amounts of amyloids and lipopolysaccharides, which might play a role in the modulation of signaling pathways and the production of proinflammatory cytokines related to the pathogenesis of Alzheimer disease. Additionally, nutrients have been shown to affect the composition of the gut microbiota as well as the formation and aggregation of cerebral amyloid-β. This suggests that modulating the gut microbiome and amyloidogenesis through specific nutritional interventions might prove to be an effective strategy to prevent or reduce the risk of Alzheimer disease. This review examines the possible role of the gut in the dissemination of amyloids, the role of the gut microbiota in the regulation of the gut–brain axis, the potential amyloidogenic properties of gut bacteria, and the possible impact of nutrients on modulation of microbiota composition and amyloid formation in relation to the pathogenesis of Alzheimer disease. metadata Pistollato, Francesca; Sumalla Cano, Sandra; Elío Pascual, Iñaki; Masias Vergara, Manuel; Giampieri, Francesca y Battino, Maurizio mail francesca.pistollato@uneatlantico.es, sandra.sumalla@uneatlantico.es, inaki.elio@uneatlantico.es, manuel.masias@uneatlantico.es, francesca.giampieri@uneatlantico.es, maurizio.battino@uneatlantico.es (2016) Role of gut microbiota and nutrients in amyloid formation and pathogenesis of Alzheimer disease. Nutrition Reviews, 74 (10). pp. 624-634. ISSN 0029-6643

S

Artículo Materias > Biomedicina
Materias > Ingeniería
Materias > Alimentación
Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Cerrado Inglés Obesity and overweight has increased in the last year and has become a pandemic disease, the result of sedentary lifestyles and unhealthy diets rich in sugars, refined starches, fats and calories. Machine learning (ML) has proven to be very useful in the scientific community, especially in the health sector. With the aim of providing useful tools to help nutritionists and dieticians, research focused on the development of ML and Deep Learning (DL) algorithms and models is searched in the literature. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol has been used, a very common technique applied to carry out revisions. In our proposal, 17 articles have been filtered in which ML and DL are applied in the prediction of diseases, in the delineation of treatment strategies, in the improvement of personalized nutrition and more. Despite expecting better results with the use of DL, according to the selected investigations, the traditional methods are still the most used and the yields in both cases fluctuate around positive values, conditioned by the databases (transformed in each case) to a greater extent than by the artificial intelligence paradigm used. Conclusions: An important compilation is provided for the literature in this area. ML models are time-consuming to clean data, but (like DL) they allow automatic modeling of large volumes of data which makes them superior to traditional statistics. metadata Ferreras, Antonio; Sumalla Cano, Sandra; Martínez-Licort, Rosmeri; Elío Pascual, Iñaki; Tutusaus, Kilian; Prola, Thomas; Vidal Mazón, Juan Luis; Sahelices, Benjamín y de la Torre Díez, Isabel mail SIN ESPECIFICAR, sandra.sumalla@uneatlantico.es, SIN ESPECIFICAR, inaki.elio@uneatlantico.es, kilian.tutusaus@uneatlantico.es, thomas.prola@uneatlantico.es, juanluis.vidal@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR (2023) Systematic Review of Machine Learning applied to the Prediction of Obesity and Overweight. Journal of Medical Systems, 47 (1). ISSN 1573-689X

T

Artículo Materias > Biomedicina
Materias > Alimentación
Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Cerrado Inglés In the last decade, specific dietary patterns, mainly characterized by high consumption of vegetables and fruits, have been proven beneficial for the prevention of both metabolic syndrome (MetS)-related dysfunctions and neurodegenerative disorders, such as Alzheimer’s disease (AD). Nowadays, neuroimaging readouts can be used to diagnose AD, investigate MetS effects on brain functionality and anatomy, and assess the effects of dietary supplementations and nutritional patterns in relation to neurodegeneration and AD-related features. Here we review scientific literature describing the use of the most recent neuroimaging techniques to detect AD- and MetS-related brain features, and also to investigate associations between consolidated dietary patterns or nutritional interventions and AD, specifically focusing on observational and intervention studies in humans. metadata Pistollato, Francesca; Sumalla Cano, Sandra; Elío Pascual, Iñaki; Masías Vergara, Manuel; Giampieri, Francesca y Battino, Maurizio mail francesca.pistollato@uneatlantico.es, sandra.sumalla@uneatlantico.es, inaki.elio@uneatlantico.es, manuel.masias@uneatlantico.es, francesca.giampieri@uneatlantico.es, maurizio.battino@uneatlantico.es (2015) The Use of Neuroimaging to Assess Associations Among Diet, Nutrients, Metabolic Syndrome, and Alzheimer’s Disease. Journal of Alzheimer's Disease, 48 (2). pp. 303-318. ISSN 13872877

U

Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Abierto Inglés Over the last decades, the Mediterranean diet gained enormous scientific, social, and commercial attention due to proven positive effects on health and undeniable taste that facilitated a widespread popularity. Researchers have investigated the role of Mediterranean-type dietary patterns on human health all around the world, reporting consistent findings concerning its benefits. However, what does truly define the Mediterranean diet? The myriad of dietary scores synthesizes the nutritional content of a Mediterranean-type diet, but a variety of aspects are generally unexplored when studying the adherence to this dietary pattern. Among dietary factors, the main characteristics of the Mediterranean diet, such as consumption of fruit and vegetables, olive oil, and cereals should be accompanied by other underrated features, such as the following: (i) specific reference to whole-grain consumption; (ii) considering the consumption of legumes, nuts, seeds, herbs and spices often untested when exploring the adherence to the Mediterranean diet; (iii) consumption of eggs and dairy products as common foods consumed in the Mediterranean region (irrespectively of the modern demonization of dietary fat intake). Another main feature of the Mediterranean diet includes (red) wine consumption, but more general patterns of alcohol intake are generally unmeasured, lacking specificity concerning the drinking occasion and intensity (i.e., alcohol drinking during meals). Among other underrated aspects, cooking methods are rather simple and yet extremely varied. Several underrated aspects are related to the quality of food consumed when the Mediterranean diet was first investigated: foods are locally produced, minimally processed, and preserved with more natural methods (i.e., fermentation), strongly connected with the territory with limited and controlled impact on the environment. Dietary habits are also associated with lifestyle behaviors, such as sleeping patterns, and social and cultural values, favoring commensality and frugality. In conclusion, it is rather reductive to consider the Mediterranean diet as just a pattern of food groups to be consumed decontextualized from the social and geographical background of Mediterranean culture. While the methodologies to study the Mediterranean diet have demonstrated to be useful up to date, a more holistic approach should be considered in future studies by considering the aforementioned underrated features and values to be potentially applied globally through the concept of a “Planeterranean” diet. metadata Godos, Justyna; Scazzina, Francesca; Paternò Castello, Corrado; Giampieri, Francesca; Quiles, José L.; Briones Urbano, Mercedes; Battino, Maurizio; Galvano, Fabio; Iacoviello, Licia; de Gaetano, Giovanni; Bonaccio, Marialaura y Grosso, Giuseppe mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, francesca.giampieri@uneatlantico.es, jose.quiles@uneatlantico.es, mercedes.briones@uneatlantico.es, maurizio.battino@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR (2024) Underrated aspects of a true Mediterranean diet: understanding traditional features for worldwide application of a “Planeterranean” diet. Journal of Translational Medicine, 22 (1). ISSN 1479-5876

Este listado fue generado el Thu Mar 28 23:52:13 2024 UTC.

<a class="ep_document_link" href="/10290/1/Influence%20of%20E-learning%20training%20on%20the%20acquisition%20of%20competences%20in%20basketball%20coaches%20in%20Cantabria.pdf"><img class="ep_doc_icon" alt="[img]" src="/style/images/fileicons/text.png" border="0"/></a>

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Influence of E-learning training on the acquisition of competences in basketball coaches in Cantabria

The main aim of this study was to analyse the influence of e-learning training on the acquisition of competences in basketball coaches in Cantabria. The current landscape of basketball coach training shows an increasing demand for innovative training models and emerging pedagogies, including e-learning-based methodologies. The study sample consisted of fifty students from these courses, all above 16 years of age (36 males, 14 females). Among them, 16% resided outside the autonomous community of Cantabria, 10% resided more than 50 km from the city of Santander, 36% between 10 and 50 km, 14% less than 10 km, and 24% resided within Santander city. Data were collected through a Google Forms survey distributed by the Cantabrian Basketball Federation to training course students. Participation was voluntary and anonymous. The survey, consisting of 56 questions, was validated by two sports and health doctors and two senior basketball coaches. The collected data were processed and analysed using Microsoft® Excel version 16.74, and the results were expressed in percentages. The analysis revealed that 24.60% of the students trained through the e-learning methodology considered themselves fully qualified as basketball coaches, contrasting with 10.98% of those trained via traditional face-to-face methodology. The results of the study provide insights into important characteristics that can be adjusted and improved within the investigated educational process. Moreover, the study concludes that e-learning training effectively qualifies basketball coaches in Cantabria.

Producción Científica

Josep Alemany Iturriaga mail josep.alemany@uneatlantico.es, Álvaro Velarde-Sotres mail alvaro.velarde@uneatlantico.es, Javier Jorge mail , Kamil Giglio mail ,

Alemany Iturriaga

<a href="/11265/1/Food%20Frontiers%20-%202024%20-%20Cassotta%20-%20Human%E2%80%90based%20new%20approach%20methodologies%20to%20accelerate%20advances%20in%20nutrition%20research.pdf" class="ep_document_link"><img class="ep_doc_icon" alt="[img]" src="/style/images/fileicons/text.png" border="0"/></a>

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Human‐based new approach methodologies to accelerate advances in nutrition research

Much of nutrition research has been conventionally based on the use of simplistic in vitro systems or animal models, which have been extensively employed in an effort to better understand the relationships between diet and complex diseases as well as to evaluate food safety. Although these models have undeniably contributed to increase our mechanistic understanding of basic biological processes, they do not adequately model complex human physiopathological phenomena, creating concerns about the translatability to humans. During the last decade, extraordinary advancement in stem cell culturing, three-dimensional cell cultures, sequencing technologies, and computer science has occurred, which has originated a wealth of novel human-based and more physiologically relevant tools. These tools, also known as “new approach methodologies,” which comprise patient-derived organoids, organs-on-chip, multi-omics approach, along with computational models and analysis, represent innovative and exciting tools to forward nutrition research from a human-biology-oriented perspective. After considering some shortcomings of conventional in vitro and vivo approaches, here we describe the main novel available and emerging tools that are appropriate for designing a more human-relevant nutrition research. Our aim is to encourage discussion on the opportunity to explore innovative paths in nutrition research and to promote a paradigm-change toward a more human biology-focused approach to better understand human nutritional pathophysiology, to evaluate novel food products, and to develop more effective targeted preventive or therapeutic strategies while helping in reducing the number and replacing animals employed in nutrition research.

Producción Científica

Manuela Cassotta mail manucassotta@gmail.com, Danila Cianciosi mail , Maria Elexpuru Zabaleta mail maria.elexpuru@uneatlantico.es, Iñaki Elío Pascual mail inaki.elio@uneatlantico.es, Sandra Sumalla Cano mail sandra.sumalla@uneatlantico.es, Francesca Giampieri mail francesca.giampieri@uneatlantico.es, Maurizio Battino mail maurizio.battino@uneatlantico.es,

Cassotta

<a class="ep_document_link" href="/11322/1/journal.pone.0298582.pdf"><img class="ep_doc_icon" alt="[img]" src="/style/images/fileicons/text.png" border="0"/></a>

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Design and development of patient health tracking, monitoring and big data storage using Internet of Things and real time cloud computing

With the outbreak of the COVID-19 pandemic, social isolation and quarantine have become commonplace across the world. IoT health monitoring solutions eliminate the need for regular doctor visits and interactions among patients and medical personnel. Many patients in wards or intensive care units require continuous monitoring of their health. Continuous patient monitoring is a hectic practice in hospitals with limited staff; in a pandemic situation like COVID-19, it becomes much more difficult practice when hospitals are working at full capacity and there is still a risk of medical workers being infected. In this study, we propose an Internet of Things (IoT)-based patient health monitoring system that collects real-time data on important health indicators such as pulse rate, blood oxygen saturation, and body temperature but can be expanded to include more parameters. Our system is comprised of a hardware component that collects and transmits data from sensors to a cloud-based storage system, where it can be accessed and analyzed by healthcare specialists. The ESP-32 microcontroller interfaces with the multiple sensors and wirelessly transmits the collected data to the cloud storage system. A pulse oximeter is utilized in our system to measure blood oxygen saturation and body temperature, as well as a heart rate monitor to measure pulse rate. A web-based interface is also implemented, allowing healthcare practitioners to access and visualize the collected data in real-time, making remote patient monitoring easier. Overall, our IoT-based patient health monitoring system represents a significant advancement in remote patient monitoring, allowing healthcare practitioners to access real-time data on important health metrics and detect potential health issues before they escalate.

Producción Científica

Md. Milon Islam mail , Imran Shafi mail , Sadia Din mail , Siddique Farooq mail , Isabel de la Torre Díez mail , Jose Breñosa mail josemanuel.brenosa@uneatlantico.es, Julio César Martínez Espinosa mail ulio.martinez@unini.edu.mx, Imran Ashraf mail ,

Islam

<a class="ep_document_link" href="/11426/1/s12967-024-05095-w.pdf"><img class="ep_doc_icon" alt="[img]" src="/style/images/fileicons/text.png" border="0"/></a>

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Underrated aspects of a true Mediterranean diet: understanding traditional features for worldwide application of a “Planeterranean” diet

Over the last decades, the Mediterranean diet gained enormous scientific, social, and commercial attention due to proven positive effects on health and undeniable taste that facilitated a widespread popularity. Researchers have investigated the role of Mediterranean-type dietary patterns on human health all around the world, reporting consistent findings concerning its benefits. However, what does truly define the Mediterranean diet? The myriad of dietary scores synthesizes the nutritional content of a Mediterranean-type diet, but a variety of aspects are generally unexplored when studying the adherence to this dietary pattern. Among dietary factors, the main characteristics of the Mediterranean diet, such as consumption of fruit and vegetables, olive oil, and cereals should be accompanied by other underrated features, such as the following: (i) specific reference to whole-grain consumption; (ii) considering the consumption of legumes, nuts, seeds, herbs and spices often untested when exploring the adherence to the Mediterranean diet; (iii) consumption of eggs and dairy products as common foods consumed in the Mediterranean region (irrespectively of the modern demonization of dietary fat intake). Another main feature of the Mediterranean diet includes (red) wine consumption, but more general patterns of alcohol intake are generally unmeasured, lacking specificity concerning the drinking occasion and intensity (i.e., alcohol drinking during meals). Among other underrated aspects, cooking methods are rather simple and yet extremely varied. Several underrated aspects are related to the quality of food consumed when the Mediterranean diet was first investigated: foods are locally produced, minimally processed, and preserved with more natural methods (i.e., fermentation), strongly connected with the territory with limited and controlled impact on the environment. Dietary habits are also associated with lifestyle behaviors, such as sleeping patterns, and social and cultural values, favoring commensality and frugality. In conclusion, it is rather reductive to consider the Mediterranean diet as just a pattern of food groups to be consumed decontextualized from the social and geographical background of Mediterranean culture. While the methodologies to study the Mediterranean diet have demonstrated to be useful up to date, a more holistic approach should be considered in future studies by considering the aforementioned underrated features and values to be potentially applied globally through the concept of a “Planeterranean” diet.

Producción Científica

Justyna Godos mail , Francesca Scazzina mail , Corrado Paternò Castello mail , Francesca Giampieri mail francesca.giampieri@uneatlantico.es, José L. Quiles mail jose.quiles@uneatlantico.es, Mercedes Briones Urbano mail mercedes.briones@uneatlantico.es, Maurizio Battino mail maurizio.battino@uneatlantico.es, Fabio Galvano mail , Licia Iacoviello mail , Giovanni de Gaetano mail , Marialaura Bonaccio mail , Giuseppe Grosso mail ,

Godos

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Isoflavones Effects on Vascular and Endothelial Outcomes: How Is the Gut Microbiota Involved?

Isoflavones are a group of (poly)phenols, also defined as phytoestrogens, with chemical structures comparable with estrogen, that exert weak estrogenic effects. These phytochemical compounds have been targeted for their proven antioxidant and protective effects. Recognizing the increasing prevalence of cardiovascular diseases (CVD), there is a growing interest in understanding the potential cardiovascular benefits associated with these phytochemical compounds. Gut microbiota may play a key role in mediating the effects of isoflavones on vascular and endothelial functions, as it is directly implicated in isoflavones metabolism. The findings from randomized clinical trials indicate that isoflavone supplementation may exert putative effects on vascular biomarkers among healthy individuals, but not among patients affected by cardiometabolic disorders. These results might be explained by the enzymatic transformation to which isoflavones are subjected by the gut microbiota, suggesting that a diverse composition of the microbiota may determine the diverse bioavailability of these compounds. Specifically, the conversion of isoflavones in equol—a microbiota-derived metabolite—seems to differ between individuals. Further studies are needed to clarify the intricate molecular mechanisms behind these contrasting results.

Producción Científica

Samuele Laudani mail , Justyna Godos mail , Giovanni Luca Romano mail , Lucia Gozzo mail , Federica Martina Di Domenico mail , Irma Dominguez Azpíroz mail irma.dominguez@unini.edu.mx, Raquel Martínez Díaz mail raquel.martinez@uneatlantico.es, Francesca Giampieri mail francesca.giampieri@uneatlantico.es, José L. Quiles mail jose.quiles@uneatlantico.es, Maurizio Battino mail maurizio.battino@uneatlantico.es, Filippo Drago mail , Fabio Galvano mail , Giuseppe Grosso mail ,

Laudani