Uninipr: Sin condiciones. Resultados ordenados -Depositado. 2024-03-28T08:13:17ZEPrintshttp://repositorio.unib.org/images/sitelogo.pnghttp://repositorio.unib.org/2024-03-26T23:30:19Z2024-03-26T23:30:22Zhttps://repositorio.unib.org/id/eprint/11426Este registro está en el repositorio con la URL: https://repositorio.unib.org/id/eprint/114262024-03-26T23:30:19ZUnderrated aspects of a true Mediterranean diet: understanding traditional features for worldwide application of a “Planeterranean” dietOver the last decades, the Mediterranean diet gained enormous scientific, social, and commercial attention due to proven positive effects on health and undeniable taste that facilitated a widespread popularity. Researchers have investigated the role of Mediterranean-type dietary patterns on human health all around the world, reporting consistent findings concerning its benefits. However, what does truly define the Mediterranean diet? The myriad of dietary scores synthesizes the nutritional content of a Mediterranean-type diet, but a variety of aspects are generally unexplored when studying the adherence to this dietary pattern. Among dietary factors, the main characteristics of the Mediterranean diet, such as consumption of fruit and vegetables, olive oil, and cereals should be accompanied by other underrated features, such as the following: (i) specific reference to whole-grain consumption; (ii) considering the consumption of legumes, nuts, seeds, herbs and spices often untested when exploring the adherence to the Mediterranean diet; (iii) consumption of eggs and dairy products as common foods consumed in the Mediterranean region (irrespectively of the modern demonization of dietary fat intake). Another main feature of the Mediterranean diet includes (red) wine consumption, but more general patterns of alcohol intake are generally unmeasured, lacking specificity concerning the drinking occasion and intensity (i.e., alcohol drinking during meals). Among other underrated aspects, cooking methods are rather simple and yet extremely varied. Several underrated aspects are related to the quality of food consumed when the Mediterranean diet was first investigated: foods are locally produced, minimally processed, and preserved with more natural methods (i.e., fermentation), strongly connected with the territory with limited and controlled impact on the environment. Dietary habits are also associated with lifestyle behaviors, such as sleeping patterns, and social and cultural values, favoring commensality and frugality. In conclusion, it is rather reductive to consider the Mediterranean diet as just a pattern of food groups to be consumed decontextualized from the social and geographical background of Mediterranean culture. While the methodologies to study the Mediterranean diet have demonstrated to be useful up to date, a more holistic approach should be considered in future studies by considering the aforementioned underrated features and values to be potentially applied globally through the concept of a “Planeterranean” diet.Justyna GodosFrancesca ScazzinaCorrado Paternò CastelloFrancesca Giampierifrancesca.giampieri@uneatlantico.esJosé L. Quilesjose.quiles@uneatlantico.esMercedes Briones Urbanomercedes.briones@uneatlantico.esMaurizio Battinomaurizio.battino@uneatlantico.esFabio GalvanoLicia IacovielloGiovanni de GaetanoMarialaura BonaccioGiuseppe Grosso2024-03-14T23:30:27Z2024-03-14T23:30:28Zhttps://repositorio.unib.org/id/eprint/11265Este registro está en el repositorio con la URL: https://repositorio.unib.org/id/eprint/112652024-03-14T23:30:27ZHuman‐based new approach methodologies to accelerate advances in nutrition researchMuch of nutrition research has been conventionally based on the use of simplistic in vitro systems or animal models, which have been extensively employed in an effort to better understand the relationships between diet and complex diseases as well as to evaluate food safety. Although these models have undeniably contributed to increase our mechanistic understanding of basic biological processes, they do not adequately model complex human physiopathological phenomena, creating concerns about the translatability to humans. During the last decade, extraordinary advancement in stem cell culturing, three-dimensional cell cultures, sequencing technologies, and computer science has occurred, which has originated a wealth of novel human-based and more physiologically relevant tools. These tools, also known as “new approach methodologies,” which comprise patient-derived organoids, organs-on-chip, multi-omics approach, along with computational models and analysis, represent innovative and exciting tools to forward nutrition research from a human-biology-oriented perspective. After considering some shortcomings of conventional in vitro and vivo approaches, here we describe the main novel available and emerging tools that are appropriate for designing a more human-relevant nutrition research. Our aim is to encourage discussion on the opportunity to explore innovative paths in nutrition research and to promote a paradigm-change toward a more human biology-focused approach to better understand human nutritional pathophysiology, to evaluate novel food products, and to develop more effective targeted preventive or therapeutic strategies while helping in reducing the number and replacing animals employed in nutrition research.Manuela Cassottamanucassotta@gmail.comDanila CianciosiMaria Elexpuru Zabaletamaria.elexpuru@uneatlantico.esIñaki Elío Pascualinaki.elio@uneatlantico.esSandra Sumalla Canosandra.sumalla@uneatlantico.esFrancesca Giampierifrancesca.giampieri@uneatlantico.esMaurizio Battinomaurizio.battino@uneatlantico.es2024-02-12T23:30:28Z2024-02-12T23:30:29Zhttps://repositorio.unib.org/id/eprint/10845Este registro está en el repositorio con la URL: https://repositorio.unib.org/id/eprint/108452024-02-12T23:30:28ZIsoflavones Effects on Vascular and Endothelial Outcomes: How Is the Gut Microbiota Involved?Isoflavones are a group of (poly)phenols, also defined as phytoestrogens, with chemical structures comparable with estrogen, that exert weak estrogenic effects. These phytochemical compounds have been targeted for their proven antioxidant and protective effects. Recognizing the increasing prevalence of cardiovascular diseases (CVD), there is a growing interest in understanding the potential cardiovascular benefits associated with these phytochemical compounds. Gut microbiota may play a key role in mediating the effects of isoflavones on vascular and endothelial functions, as it is directly implicated in isoflavones metabolism. The findings from randomized clinical trials indicate that isoflavone supplementation may exert putative effects on vascular biomarkers among healthy individuals, but not among patients affected by cardiometabolic disorders. These results might be explained by the enzymatic transformation to which isoflavones are subjected by the gut microbiota, suggesting that a diverse composition of the microbiota may determine the diverse bioavailability of these compounds. Specifically, the conversion of isoflavones in equol—a microbiota-derived metabolite—seems to differ between individuals. Further studies are needed to clarify the intricate molecular mechanisms behind these contrasting results.Samuele LaudaniJustyna GodosGiovanni Luca RomanoLucia GozzoFederica Martina Di DomenicoIrma Dominguez Azpírozirma.dominguez@unini.edu.mxRaquel Martínez Díazraquel.martinez@uneatlantico.esFrancesca Giampierifrancesca.giampieri@uneatlantico.esJosé L. Quilesjose.quiles@uneatlantico.esMaurizio Battinomaurizio.battino@uneatlantico.esFilippo DragoFabio GalvanoGiuseppe Grosso2024-02-12T23:30:25Z2024-02-12T23:30:28Zhttps://repositorio.unib.org/id/eprint/10840Este registro está en el repositorio con la URL: https://repositorio.unib.org/id/eprint/108402024-02-12T23:30:25ZMediterranean Diet and Sleep Features: A Systematic Review of Current EvidenceThe prevalence of sleep disorders, characterized by issues with quality, timing, and sleep duration is increasing globally. Among modifiable risk factors, diet quality has been suggested to influence sleep features. The Mediterranean diet is considered a landmark dietary pattern in terms of quality and effects on human health. However, dietary habits characterized by this cultural heritage should also be considered in the context of overall lifestyle behaviors, including sleep habits. This study aimed to systematically revise the literature relating to adherence to the Mediterranean diet and sleep features in observational studies. The systematic review comprised 23 reports describing the relation between adherence to the Mediterranean diet and different sleep features, including sleep quality, sleep duration, daytime sleepiness, and insomnia symptoms. The majority of the included studies were conducted in the Mediterranean basin and reported a significant association between a higher adherence to the Mediterranean diet and a lower likelihood of having poor sleep quality, inadequate sleep duration, excessive daytime sleepiness or symptoms of insomnia. Interestingly, additional studies conducted outside the Mediterranean basin showed a relationship between the adoption of a Mediterranean-type diet and sleep quality, suggesting that biological mechanisms sustaining such an association may exist. In conclusion, current evidence suggests a relationship between adhering to the Mediterranean diet and overall sleep quality and different sleep parameters. The plausible bidirectional association should be further investigated to understand whether the promotion of a healthy diet could be used as a tool to improve sleep quality.Justyna GodosRaffaele FerriGiuseppe LanzaFilippo CaraciAngel Olider Rojas Vistorteangel.rojas@uneatlantico.esVanessa Yélamos Torresvanessa.yelamos@funiber.orgGiuseppe GrossoSabrina Castellano2023-12-13T23:30:14Z2023-12-13T23:30:15Zhttps://repositorio.unib.org/id/eprint/239Este registro está en el repositorio con la URL: https://repositorio.unib.org/id/eprint/2392023-12-13T23:30:14ZMLS Health and Nutrition ResearchLa revista MLS Health and Nutrition Research nace como una publicación semestral con el objetivo de publicar artículos originales de investigación y de revisión tanto en áreas básicas como aplicadas y metodológicas que supongan una contribución científica al progreso de cualquier ámbito de la salud y nutrición como objetivo principal. Los artículos incluidos en esta revista se publican en español, portugués e inglés. La vocación internacional de esta revista promueve la difusión del conocimiento en sus diferentes áreas.make_name_string expected hash referencemls@devnull.funiber.org2023-11-16T23:30:24Z2023-11-16T23:30:24Zhttps://repositorio.unib.org/id/eprint/2029Este registro está en el repositorio con la URL: https://repositorio.unib.org/id/eprint/20292023-11-16T23:30:24ZPrograma de Transferencia de Embriones Bovinos de Especialidad Cárnica, Elaborados a partir de la Técnica Fertilización In-Vitro para Pequeños y Medianos Ganaderos del Departamento del HuilaPrograma de transferencia de embriones bovinos de especialidad cárnica, elaborados a partir de la técnica fertilización in-vitro para pequeños y medianos ganaderos del Departamento del Huila. Dentro la seguridad alimentaria, la proteína roja (carne), es una fuente esencial de la dieta humana; para llegar a ella, los sistemas ganaderos, como ocurre en el departamento del Huila, no están haciendo un manejo equilibrado en la explotación ganadera; que mayoritariamente es de doble propósito, y tan solo un 5% destinada a ceba; generando impactos negativos ambientales y bajos rendimientos en la productividad cárnica, al no utilizar razas especializadas para la producción de carne. Por eso, el objetivo principal de este trabajo consistió en diseñar un programa transferencia de embriones bovinos de especialidad cárnica, elaborados a partir de la técnica Fertilización In-vitro (FIV) para pequeños y medianos ganaderos en el departamento del Huila. Fue necesario reconocer los grupos poblaciones influyentes y dependientes de la actividad ganadera; las razas especializadas de ganado vacuno en la producción de carne, y las técnicas de reproducción bovina. La investigación fue documental tipo meta análisis con énfasis cualitativo descriptivo explicativo. En sus resultados se encontró: déficit de 10.78 kg/persona año, de suministro de carne; el 59% del ganado sacrificado, son hembras, pesan menos que el macho; baja productividad animal y rendimiento cárnico; ciclo ganadero largo entre 37 y 42 meses. Ante esa situación, se diseñó el programa FIVTEBEC-DSH Versión 1-2020, donde se establecieron unas fichas protocolarias para ser desarrolladas en cinco etapas: Selección y compromiso ganaderos de la región; procedimentales para la selección de bovinos; de obtención y clasificación de los embriones; de producción in vitro, y de la transferencia de embriones, empleándose razas especializadas de carne como: Brahman Rojo y Blanco, Simmental y Simbrah 5/8-3/8.Arlinson González Gonzálezargoz2050@gmail.com2023-11-16T23:30:22Z2023-11-16T23:30:22Zhttps://repositorio.unib.org/id/eprint/2010Este registro está en el repositorio con la URL: https://repositorio.unib.org/id/eprint/20102023-11-16T23:30:22ZDesperdicios de producción en el proceso de preparación de canastas agroecológicas del centro de acopio de productos agropecuarios de la compañía de economía mixta AGROAZUAY GPA, en la ciudad de Cuenca, EcuadorLa identificación de desperdicios de producción o actividades que afectan a los procesos de producción, con la finalidad de reducirlos o eliminarlos, es un esfuerzo que las organizaciones, de todo tipo, realizan para mejorar su sistema de producción, incrementar su rentabilidad y productividad, y además reducir costos. En este sentido y con base en lo expuesto, en este proyecto de investigación de diseño no experimental, con un enfoque cualitativo y cuantitativo, de tipo documental, descriptivo y evaluativo, se realizará un trabajo de observación en el lugar de los hechos con el fin de identificar los desperdicios de producción (sobreproducción, movimiento, espera, transporte, sobre proceso, stock o inventario, defectos) presentes en el proceso de preparación de canastas agroecológicas del Centro de Acopio de Productos Agropecuarios de la Compañía de Economía Mixta AGROAZUAY GPA, en la ciudad de Cuenca, Ecuador, así como, describir las características que acompañan a estos desperdicios, y a partir de esto, analizar los efectos de los desperdicios identificados en el proceso de estudio. Una vez situados en este punto y como parte complementaria de la investigación, se diseñará una propuesta para reducir estos desperdicios de producción que se encuentran presentes en el proceso sobre el cual se investiga.Pablo Humberto Rea Parrapablorhea@hotmail.com2023-11-03T23:30:32Z2023-11-03T23:30:32Zhttps://repositorio.unib.org/id/eprint/1918Este registro está en el repositorio con la URL: https://repositorio.unib.org/id/eprint/19182023-11-03T23:30:32ZEliminación de los desechos industriales generados en la avicultura debido a la utilización de papel en la recepción de pollitos BB, mediante la incorporación al material de cama.Esta investigación se realizó en la provincia de Santo domingo de los Tsáchilas – Ecuador, en una granja avícola de 8 galpones de pollo de engorde con una capacidad de 320000 pollos. El objetivo principal fue la eliminación de los desechos industriales avícolas puesto que durante la crianza de pollos de engorde se utiliza papel periódico en la recepción de las aves desde su llegada hasta aproximadamente el segundo o tercer día de alojamiento en galpones, el uso de este papel es para suministrar y dar accesibilidad a los pollitos bebe al alimento logrando así desarrollar su potencial desde los primeros días de vida; a partir del segundo o tercer día el papel utilizado en la recepción se transforma en un desecho industrial ya que este se lo retira de los galpones para evitar empastamientos en las camas y posibles lesiones en las patas de las aves. La prueba se realizó comparando 8 galpones de producción de pollos de engorde de los cuales en 4 galpones se retiró el papel generando desechos y 4 galpones se procedió a incorporar el papel al material de cama eliminando los desechos industriales avícolas. Se analizaron variables como la cantidad de desechos generados, los costos que involucran en cada tratamiento y la generación de impacto ambiental a las cuales se realizó un análisis descriptivo debido al interés del tema; por otro lado, para las variables de ambiente, como mediciones de amoniaco y humedad, así como para los parámetros productivos o zootécnicos se realizó un análisis de varianza para medir medias de los tratamientos y observar si existen diferencias significativas. Se obtuvo varios beneficios con el aprovechamiento del papel al incorporarlo al material de cama, el principal no generar contaminación e impacto ambiental, no llenar espacios en vertederos lo cual a la par es un impacto social positivo ya que se dispondría de estos espacios para los desechos de la comunidad, por otro lado los avicultores ahorran en costos como transporte de desechos, pagos en vertederos o municipios, menor mano de obra por actividades como el retiro de papel y se demostró que la incorporación de papel al material de cama no afecta en los resultados zootécnicos o productivos de las aves.Edison Paúl Pazmiño Valenciapaulsin_pv@hotmail.com2023-10-25T23:30:22Z2023-10-25T23:30:22Zhttps://repositorio.unib.org/id/eprint/9375Este registro está en el repositorio con la URL: https://repositorio.unib.org/id/eprint/93752023-10-25T23:30:22ZCan alpha‐linolenic acid be a modulator of “cytokine storm,” oxidative stress and immune response in SARS‐CoV‐2 infection?Alpha-linolenic acid (ALA) is a long-chain polyunsaturated essential fatty acid of the Ω3 series found mainly in vegetables, especially in the fatty part of oilseeds, dried fruit, berries, and legumes. It is very popular for its preventive use in several diseases: It seems to reduce the risk of the onset or decrease some phenomena related to inflammation, oxidative stress, and conditions of dysregulation of the immune response. Recent studies have confirmed these unhealthy situations also in patients with severe coronavirus disease 2019 (COVID-19). Different findings (in vitro, in vivo, and clinical ones), summarized and analyzed in this review, have showed an important role of ALA in other various non-COVID physiological and pathological situations against “cytokines storm,” chemokines secretion, oxidative stress, and dysregulation of immune cells that are also involved in the infection of the 2019 novel coronavirus. According to the effects of ALA against all the aforementioned situations (also present in patients with a severe clinical picture of severe acute respiratory syndrome-(CoV-2) infection), there may be the biologic plausibility of a prophylactic effect of this compound against COVID-19 symptoms and fatality.Danila CianciosiYasmany Armas DiazAntonio Vittorino GaddiFabio CapelloMaria Teresa SavoRamón Pali-Casanovaramon.pali@unini.edu.mxJulio César Martínez Espinosaulio.martinez@unini.edu.mxAlina Eugenia Pascual Barreraalina.pascual@unini.edu.mxMaria‐Dolores Navarro‐HortalLingmin TianWeibin BaiFrancesca Giampierifrancesca.giampieri@uneatlantico.esMaurizio Battino2023-10-20T23:30:19Z2023-10-20T23:30:19Zhttps://repositorio.unib.org/id/eprint/980Este registro está en el repositorio con la URL: https://repositorio.unib.org/id/eprint/9802023-10-20T23:30:19ZAvaliação da utilização de pivô central na irrigação do cultivo do arroz no município de Uruguaiana-RS: um estudo de casoO tema deste estudo está pautado em um estudo de caso na avaliação da utilização do pivô central na irrigação do cultivo do arroz no município de Uruguaiana-RS. Para entender o problema principal do estudo que é a falta e ou dificuldade de irrigação do cultivo de arroz onde existe escassez de água, pretendendo estudar a utilização do pivô central e sua efetividade nos cultivos. Nos últimos anos estamos percebendo com maior intensidade que a escassez de água tem prejudicado diversas regiões de nosso País na irrigação das plantações que demandam de maior irrigação como o cultivo do arroz quando existe uma maior necessidade de demanda de água para sua irrigação. Este trabalho teve por objetivo geral avaliar a utilização do pivô central na irrigação do cultivo de arroz. E como objetivos específicos: analisar as questões econômicas, na relação investimento, lucro e prejuízo com o uso do pivô central, analisar os fatores ambientais, considerando, tanto o modo de instalação e funcionamento do equipamento, analisar se há o uso racional e responsável dos recursos hídricos. A metodologia utilizada foi de pesquisa bibliográfica e estudo de caso de observação de funcionamento do sistema de pivô central de irrigação. E como resultado percebe-se que este sistema quando em bom funcionamento pode colaborar significativamente na economia de energia elétrica, considerando um retorno importante para novos investimentos em sistemas de irrigação e obteve-se como conclusão principal que a utilização do pivô central se mostra como um grande potencial de economia e rentabilidade nos cultivos de arroz, podendo apresentar também um retorno do capital investido.Guilherme dos Santos Campãoguicampao@gmail.com2023-10-16T23:30:21Z2023-10-16T23:30:21Zhttps://repositorio.unib.org/id/eprint/9217Este registro está en el repositorio con la URL: https://repositorio.unib.org/id/eprint/92172023-10-16T23:30:21ZBetalains: The main bioactive compounds of Opuntia spp and their possible health benefits in the Mediterranean dietBetalains are water-soluble, nitrogen-containing vacuolar pigment and can be divided into two subclasses: the yellow – orange betaxanthins and the red – violet betacyanin. These pigments can be found mainly in Latin America, but also in some parts of Asia, Africa, Australia and in the Mediterranean area. In this work an overview related with the status of research about betalains extracted from Opuntia spp and the enforces made to evaluate their positive incidence in the human body is provided. Several studies enhance their anticancer, anti-inflammatory and antioxidant properties. They also exhibit antimicrobial and antidiabetic effect. Taking into account these properties, betalains seem to be a promising natural alternative as a colorant to replace the synthetic ones in the food additive industry. In addition, the use of Opuntia spp fruits as possible colorant sources in the Food Industry, may contribute positively to the sustainable development in semi-arid regions.Yasmany Armas DiazZexiu QiBei YangNohora Milena Martínez Lópeznohora.martinez@uneatlantico.esMercedes Briones Urbanomercedes.briones@uneatlantico.esDanila Cianciosi2023-09-26T23:30:16Z2023-09-26T23:30:17Zhttps://repositorio.unib.org/id/eprint/2710Este registro está en el repositorio con la URL: https://repositorio.unib.org/id/eprint/27102023-09-26T23:30:16ZAspectos antropométricos, físicos, nutricionales y psicológicos en deportistas federados y escolaresLa Actividad Física (AF) es muy importante en la edad escolar por ser precursora de hábitos saludables en la vida adulta. Asociada a numerosos beneficios sobre la salud y a la reducción de enfermedades no transmisibles. A nivel psicológico se la asocia con un menor nivel de ansiedad y mejor autoconfianza. Además, la AF se relaciona con la alimentación, donde la Dieta Mediterránea (DM) es esencial para tener un estilo de vida saludable. La investigación consta de dos estudios descriptivo-transversales, que analizarán variables relacionadas con la AF, la salud y los estados de ánimo. La muestra ha estado compuesta por 485 escolares de Infantil, Primaria y Secundaria: •Estudio 1: Se han descrito los niveles y diferencias encontradas con rela-ción al deporte practicado. A su vez, se midieron las siguientes variables: el Índice Cintura Cadera (ICC), Índice Cintura Muslo (ICM), Índice de Masa Corporal (IMC), y porcentaje de grasa corporal; los deportistas auto informaron respecto al volumen de actividad física practicada (VAFP) mediante un cuestionario Sociodemográfico, y la Adherencia a la Dieta Mediterránea (ADM) con el Índice de calidad de la Dieta Mediterránea (KIDMED). La aptitud cardiorrespiratoria (AC) mediante el test de Course Navette. •Estudio 2: Se han descrito y comparado los estados de ánimo, utilizando un cuestionario de autovaloración psicológica (POMS) en relación al deporte practicado y respecto a si son deportistas federados o escolares. En ambos estudios se analizaron tres deportes: atletismo, fútbol y hockey hierba. En los resultados se ha encontrado una asociación positiva entre la práctica de deporte federado y las variables analizadas. Es decir, que realizar dicha práctica es sinónimo de salud, en lo que se refiere a mejores valores en variables relacionadas con la condición física, la alimentación o perfil de estado de ánimo.Javier Fernández Garcíajavier.fernandez@doctorado.unib.org2023-07-06T23:30:07Z2023-07-06T23:30:07Zhttps://repositorio.unib.org/id/eprint/7844Este registro está en el repositorio con la URL: https://repositorio.unib.org/id/eprint/78442023-07-06T23:30:07ZCan the phenolic compounds of Manuka honey chemosensitize colon cancer stem cells? A deep insight into the effect on chemoresistance and self-renewalManuka honey, which is rich in pinocembrin, quercetin, naringenin, salicylic, p-coumaric, ferulic, syringic and 3,4-dihydroxybenzoic acids, has been shown to have pleiotropic effects against colon cancer cells. In this study, potential chemosensitizing effects of Manuka honey against 5-Fluorouracil were investigated in colonspheres enriched with cancer stem cells (CSCs), which are responsible for chemoresistance. Results showed that 5-Fluorouracil increased when it was combined with Manuka honey by downregulating the gene expression of both ATP-binding cassette sub-family G member 2, an efflux pump and thymidylate synthase, the main target of 5-Fluorouracil which regulates the ex novo DNA synthesis. Manuka honey was associated with decreased self-renewal ability by CSCs, regulating expression of several genes in Wnt/β-catenin, Hedgehog and Notch pathways. This preliminary study opens new areas of research into the effects of natural compounds in combination with pharmaceuticals and, potentially, increase efficacy or reduce adverse effects.Danila CianciosiYasmany Armas DiazJosé M. Alvarez-SuarezXiumin ChenDi ZhangNohora Milena Martínez Lópeznohora.martinez@uneatlantico.esMercedes Briones Urbanomercedes.briones@uneatlantico.esJosé L. Quilesjose.quiles@uneatlantico.esAdolfo AmiciMaurizio Battinomaurizio.battino@uneatlantico.esFrancesca Giampierifrancesca.giampieri@uneatlantico.es2023-02-17T23:30:07Z2023-02-17T23:30:08Zhttps://repositorio.unib.org/id/eprint/5929Este registro está en el repositorio con la URL: https://repositorio.unib.org/id/eprint/59292023-02-17T23:30:07ZIn Vivo Anti-Alzheimer and Antioxidant Properties of Avocado (Persea americana Mill.) Honey from Southern SpainThere is growing evidence that Alzheimer’s disease (AD) can be prevented by reducing risk factors involved in its pathophysiology. Food-derived bioactive molecules can help in the prevention and reduction of the progression of AD. Honey, a good source of antioxidants and bioactive molecules, has been tied to many health benefits, including those from neurological origin. Monofloral avocado honey (AH) has recently been characterized but its biomedical properties are still unknown. The aim of this study is to further its characterization, focusing on the phenolic profile. Moreover, its antioxidant capacity was assayed both in vitro and in vivo. Finally, a deep analysis on the pathophysiological features of AD such as oxidative stress, amyloid-β aggregation, and protein-tau-induced neurotoxicity were evaluated by using the experimental model C. elegans. AH exerted a high antioxidant capacity in vitro and in vivo. No toxicity was found in C. elegans at the dosages used. AH prevented ROS accumulation under AAPH-induced oxidative stress. Additionally, AH exerted a great anti-amyloidogenic capacity, which is relevant from the point of view of AD prevention. AH exacerbated the locomotive impairment in a C. elegans model of tauopathy, although the real contribution of AH remains unclear. The mechanisms under the observed effects might be attributed to an upregulation of daf-16 as well as to a strong ROS scavenging activity. These results increase the interest to study the biomedical applications of AH; however, more research is needed to deepen the mechanisms under the observed effectsJose M. Romero-MárquezMaría D. Navarro-HortalFrancisco J. OrantesAdelaida Esteban-MuñozCristina Mazas Pérez-Oleagacristina.mazas@uneatlantico.esMaurizio Battinomaurizio.battino@uneatlantico.esCristina Sánchez-GonzálezLorenzo Rivas-GarcíaFrancesca Giampierifrancesca.giampieri@uneatlantico.esJosé L. Quilesjose.quiles@uneatlantico.esTamara Y. Forbes-Hernandeztamara.forbes@unini.edu.mx2023-02-03T23:30:07Z2023-02-03T23:30:07Zhttps://repositorio.unib.org/id/eprint/5710Este registro está en el repositorio con la URL: https://repositorio.unib.org/id/eprint/57102023-02-03T23:30:07ZDeterminación de e. Coli, hongos y levaduras en la harina proveniente de las cascarillas de dos variedades de cacao en EcuadorEn la presente investigación, se evaluó la presencia de E. coli, hongos y levaduras en la harina proveniente de las cascarillas de las variedades de cacao Nacional Arriba y el cacao CCN51 en Ecuador, para su uso en los procesos de elaboración de galletas, panes y pasteles. Se tomaron cinco muestras de 2000 g cada una, de 5 lotes diferentes para cada variedad de cacao en dos industrias cacaoteras en la provincia del Guayas. Se realizó la molienda con un molino marca Oster, se homogenizaron las muestras y se empacaron 500 g de las cáscaras molidas de cada variedad en fundas de polietileno de baja densidad, para poder realizar los análisis microbiológicos. Las muestras fueron enviadas a un laboratorio certificado para realizar los análisis correspondientes. Debido a que no existe alguna norma de calidad para la harina proveniente de cascarillas de cacao en Ecuador, se aplicaron las normas INEN 616 e INEN 621, las cuales definen los requisitos que debe cumplir la harina de trigo y los chocolates respetivamente para que sea apta para el consumo humano, comprobando que la harina proveniente de las cascarillas de ambas variedades cumple con los criterios establecidos en estas normas.Ahmed El SalousAlina Eugenia Pascual Barreraalina.pascual@unini.edu.mx2023-01-23T23:30:04Z2023-01-23T23:30:04Zhttps://repositorio.unib.org/id/eprint/5529Este registro está en el repositorio con la URL: https://repositorio.unib.org/id/eprint/55292023-01-23T23:30:04ZAnthocyanins: what do we know until now?Diets enriched in plant-based foods are associated with the maintenance of a good well-being and with the prevention of many non-communicable diseases. The health effects of fruits and vegetables consumption are mainly due to the presence of micronutrients, including vitamins and minerals, and polyphenols, plant secondary metabolites. One of the most important classes of phenolic compounds are anthocyanins, that confer the typical purple-red color to many foods, such as berries, peaches, plums, red onions, purple corn, eggplants, as well as purple carrots, sweet potatoes and red cabbages, among others. This commentary aims to briefly highlight the progress made by science in the last years, focusing on some unexpected aspects related with anthocyanins, such as their bioavailability, their health effects and their relationship with gut microbiotaFrancesca Giampierifrancesca.giampieri@uneatlantico.esDanila CianciosiJosé M. Alvarez-SuarezJosé L. Quilesjose.quiles@uneatlantico.esTamara Y. Forbes-HernándezMaría D. Navarro-HortalMichele MachìRamón Pali-Casanovaramon.pali@unini.edu.mxJulio César Martínez Espinosaulio.martinez@unini.edu.mxXiumin ChenDi ZhangWeibin BaiTian LingminBruno MezzettiMaurizio Battinomaurizio.battino@uneatlantico.esYasmany Armas Diaz2023-01-13T23:30:04Z2023-01-13T23:30:04Zhttps://repositorio.unib.org/id/eprint/5420Este registro está en el repositorio con la URL: https://repositorio.unib.org/id/eprint/54202023-01-13T23:30:04ZSystematic Review of Machine Learning applied to the Prediction of Obesity and OverweightObesity and overweight has increased in the last year and has become a pandemic disease, the result of sedentary lifestyles and unhealthy diets rich in sugars, refined starches, fats and calories. Machine learning (ML) has proven to be very useful in the scientific community, especially in the health sector. With the aim of providing useful tools to help nutritionists and dieticians, research focused on the development of ML and Deep Learning (DL) algorithms and models is searched in the literature. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol has been used, a very common technique applied to carry out revisions. In our proposal, 17 articles have been filtered in which ML and DL are applied in the prediction of diseases, in the delineation of treatment strategies, in the improvement of personalized nutrition and more. Despite expecting better results with the use of DL, according to the selected investigations, the traditional methods are still the most used and the yields in both cases fluctuate around positive values, conditioned by the databases (transformed in each case) to a greater extent than by the artificial intelligence paradigm used. Conclusions: An important compilation is provided for the literature in this area. ML models are time-consuming to clean data, but (like DL) they allow automatic modeling of large volumes of data which makes them superior to traditional statistics.Antonio FerrerasSandra Sumalla Canosandra.sumalla@uneatlantico.esRosmeri Martínez-LicortIñaki Elío Pascualinaki.elio@uneatlantico.esKilian Tutusauskilian.tutusaus@uneatlantico.esThomas Prolathomas.prola@uneatlantico.esJuan Luis Vidal Mazónjuanluis.vidal@uneatlantico.esBenjamín SahelicesIsabel de la Torre Díez2023-01-12T23:30:06Z2023-01-12T23:30:06Zhttps://repositorio.unib.org/id/eprint/5399Este registro está en el repositorio con la URL: https://repositorio.unib.org/id/eprint/53992023-01-12T23:30:06ZFuncionalidad motriz, estado nutricional e índices antropométricos de riesgo cardiometabólico en adolescentes chilenos de 12 a 15 añosEl presente estudio tiene como objetivo determinar las relaciones entre los valores de funcionalidad motriz, estado nutricional e índices antropométricos de salud en adolescentes chilenos de 12 a 15 años. Estudio de corte transversal con una muestra no probabilística y por conveniencia, con una muestra final de 384 escolares (13,04 ± 0,85 años). Todos los participantes asistieron a dos sesiones de evaluación, donde se les realizó un registro de la historia clínica y una examinación física médica. En la segunda sesión, se realizaron evaluaciones antropométricas y las pruebas consideradas en la batería Functional Movement Screen (FMS). Los resultados muestran un 46,62% de los adolescentes posee sobrepeso y/u obesidad. El score total de FMS fue de 14,29±2,85 y se encontraron diferencias significativas en el IMC (índice de masa corporal) p=0,000 y en el peso p=0,002 según dependencia administrativa. Existe una relación entre FMS y PC (Perímetro de cintura), IMC e ICE (índice cintura estatura) (r=-0,31**p<0,003, r=-0,14**p<0,004 y r=0,38**p<0,003 respectivamente). También se encontró que aquellos escolares que presentan riesgo cardio metabólico también ostentarían un mayor riesgo relacionado con una baja calidad de la funcionalidad motriz. Se concluye que los niveles elevados de parámetros antropométricos de riesgo cardiovascular en especial el exceso de peso y el elevado perímetro de cintura se relacionan con una deficiente funcionalidad motriz. Y por otra parte se generan problemáticas cardiovasculares en esta etapa de la vida sin mayor distinción de sexo y dependencia administraba de los colegios, lo cual hace ver que la mal nutrición y la falta de actividad física impacta de manera transversal a la sociedad.Carolina Rodríguez Canalescarolina.rodriguez@unini.orgClaudio Hinojosa TorresEugenio Merellano-NavarroFernando Barraza-GómezGernot Hecht-Chau2023-01-11T23:30:05Z2023-07-17T23:30:14Zhttps://repositorio.unib.org/id/eprint/5365Este registro está en el repositorio con la URL: https://repositorio.unib.org/id/eprint/53652023-01-11T23:30:05ZPrickly pear fruits from "Opuntia ficus-indica" varieties as a source of potential bioactive compounds in the Mediterranean dietCactus has been used in traditional folk medicine because of its role in treating a number of diseases and conditions. Prickly pear fruit is an excellent source of secondary metabolites (i.e., betalains, flavonoids, and ascorbic acid) with health-promoting properties against many common human diseases, including diabetes, hypertension, hypercholesterolemia, rheumatic pain, gastric mucosa diseases and asthma. In addition, prickly pears are potential candidates for the development of low-cost functional foods because they grow with low water requirements in arid regions of the world. This review describes the main bioactive compounds found in this fruit and shows the in vitro and some clinical studies about the fruit of most important cactus (Opuntia ficus-indica) and its relationship with some chronic diseases. Even though a lot of effort have been done to study the relationship between this fruit and the human health, more studies on Opuntia ficus-indica could help better understand its pharmacological mechanism of action to provide clear scientific evidence to explain its traditional uses, and to identify its therapeutic potential in other diseases.Yasmany Armas DiazMichele MachìAlessia SalinariCristina Mazas Pérez-Oleagacristina.mazas@uneatlantico.esNohora Milena Martínez Lópeznohora.martinez@uneatlantico.esMercedes Briones Urbanomercedes.briones@uneatlantico.esDanila Cianciosi2022-10-14T23:30:04Z2023-03-09T23:30:11Zhttps://repositorio.unib.org/id/eprint/96Este registro está en el repositorio con la URL: https://repositorio.unib.org/id/eprint/962022-10-14T23:30:04ZRole of gut microbiota and nutrients in amyloid formation and pathogenesis of Alzheimer diseaseIt has been hypothesized that alterations in the composition of the gut microbiota might be associated with the onset of certain human pathologies, such as Alzheimer disease, a neurodegenerative syndrome associated with cerebral accumulation of amyloid-β fibrils. It has been shown that bacteria populating the gut microbiota can release significant amounts of amyloids and lipopolysaccharides, which might play a role in the modulation of signaling pathways and the production of proinflammatory cytokines related to the pathogenesis of Alzheimer disease. Additionally, nutrients have been shown to affect the composition of the gut microbiota as well as the formation and aggregation of cerebral amyloid-β. This suggests that modulating the gut microbiome and amyloidogenesis through specific nutritional interventions might prove to be an effective strategy to prevent or reduce the risk of Alzheimer disease. This review examines the possible role of the gut in the dissemination of amyloids, the role of the gut microbiota in the regulation of the gut–brain axis, the potential amyloidogenic properties of gut bacteria, and the possible impact of nutrients on modulation of microbiota composition and amyloid formation in relation to the pathogenesis of Alzheimer disease.Francesca Pistollatofrancesca.pistollato@uneatlantico.esSandra Sumalla Canosandra.sumalla@uneatlantico.esIñaki Elío Pascualinaki.elio@uneatlantico.esManuel Masias Vergaramanuel.masias@uneatlantico.esFrancesca Giampierifrancesca.giampieri@uneatlantico.esMaurizio Battinomaurizio.battino@uneatlantico.es2022-09-29T03:04:24Z2022-09-29T03:04:25Zhttps://repositorio.unib.org/id/eprint/3718Este registro está en el repositorio con la URL: https://repositorio.unib.org/id/eprint/37182022-09-29T03:04:24ZEating Habits Associated with Nutrition-Related Knowledge among University Students Enrolled in Academic Programs Related to Nutrition and Culinary Arts in Puerto RicoUniversity students frequently develop unhealthy eating habits. However, it is unknown if students enrolled in academic programs related to nutrition and culinary arts have healthier eating habits. We evaluated the relationship of eating habits and nutritional status of students in academic programs with knowledge on nutrition, as well as cooking methods and techniques. A descriptive cross-sectional study was conducted in spring of 2019, while we completed a survey measuring eating habits and knowledge on nutrition, as well as cooking methods and techniques. Anthropometric measurements were collected for nutritional status estimation. The non-probabilistic convenience sample comprised 93 students pursuing degrees at Universidad Ana G. Mendez, Puerto Rico. Inadequate body mass index (BMI) was observed in 59% of the students. Eating habits, knowledge on nutrition, and knowledge on cooking methods and techniques were inadequate in 86%, 68%, and 41% of the population, respectively. Eating habits were associated with knowledge on nutrition and academic program, but not with knowledge on cooking methods and techniques. Most students reported having inadequate eating habits and BMI. Nutrition and dietetics students had the best knowledge on nutrition compared to culinary management students, a majority of whom had inadequate knowledge. We can conclude that there are other factors inherent to students’ life that may have a stronger influence on eating habitsChristian Rivera MedinaMercedes Briones Urbanomercedes.briones@uneatlantico.esAixa de Jesús EspinosaÁngel Toledo López2022-03-14T23:55:04Z2022-03-14T23:55:04Zhttps://repositorio.unib.org/id/eprint/536Este registro está en el repositorio con la URL: https://repositorio.unib.org/id/eprint/5362022-03-14T23:55:04ZThe Use of Neuroimaging to Assess Associations Among Diet, Nutrients, Metabolic Syndrome, and Alzheimer’s DiseaseIn the last decade, specific dietary patterns, mainly characterized by high consumption of vegetables and fruits, have been proven beneficial for the prevention of both metabolic syndrome (MetS)-related dysfunctions and neurodegenerative disorders, such as Alzheimer’s disease (AD). Nowadays, neuroimaging readouts can be used to diagnose AD, investigate MetS effects on brain functionality and anatomy, and assess the effects of dietary supplementations and nutritional patterns in relation to neurodegeneration and AD-related features. Here we review scientific literature describing the use of the most recent neuroimaging techniques to detect AD- and MetS-related brain features, and also to investigate associations between consolidated dietary patterns or nutritional interventions and AD, specifically focusing on observational and intervention studies in humans.Francesca Pistollatofrancesca.pistollato@uneatlantico.esSandra Sumalla Canosandra.sumalla@uneatlantico.esIñaki Elío Pascualinaki.elio@uneatlantico.esManuel Masías Vergaramanuel.masias@uneatlantico.esFrancesca Giampierifrancesca.giampieri@uneatlantico.esMaurizio Battinomaurizio.battino@uneatlantico.es