Items where Author is "Tutusaus, Kilian"

Article Subjects > Biomedicine
Subjects > Engineering Europe University of Atlantic > Research > Scientific Production
Fundación Universitaria Internacional de Colombia > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Articles and Books
Universidad Internacional do Cuanza > Research > Scientific Production
University of La Romana > Research > Scientific Production Open English Histopathological evaluation is necessary for the diagnosis and grading of prostate cancer, which is still one of the most common cancers in men globally. Traditional evaluation is time-consuming, prone to inter-observer variability, and challenging to scale. The clinical usefulness of current AI systems is limited by the need for comprehensive pixel-level annotations. The objective of this research is to develop and evaluate a large-scale benchmarking study on a weakly supervised deep learning framework that minimizes the need for annotation and ensures interpretability for automated prostate cancer diagnosis and International Society of Urological Pathology (ISUP) grading using whole slide images (WSIs). This study rigorously tested six cutting-edge multiple instance learning (MIL) architectures (CLAM-MB, CLAM-SB, ILRA-MIL, AC-MIL, AMD-MIL, WiKG-MIL), three feature encoders (ResNet50, CTransPath, UNI2), and four patch extraction techniques (varying sizes and overlap) using the PANDA dataset (10,616 WSIs), yielding 72 experimental configurations. The methodology used distributed cloud computing to process over 31 million tissue patches, implementing advanced attention mechanisms to ensure clinical interpretability through Grad-CAM visualizations. The optimum configuration (UNI2 encoder with ILRA-MIL, 256 256 patches, 50% overlap) achieved 78.75% accuracy and 90.12% quadratic weighted kappa (QWK), outperforming traditional methods and approaching expert pathologist-level diagnostic capability. Overlapping smaller patches offered the best balance of spatial resolution and contextual information, while domain-specific foundation models performed noticeably better than generic encoders. This work is the first large-scale, comprehensive comparison of weekly supervised MIL methods for prostate cancer diagnosis and grading. The proposed approach has excellent clinical diagnostic performance, scalability, practical feasibility through cloud computing, and interpretability using visualization tools. metadata Butt, Naveed Anwer; Sarwat, Dilawaiz; Delgado Noya, Irene; Tutusaus, Kilian; Samee, Nagwan Abdel and Ashraf, Imran mail UNSPECIFIED, UNSPECIFIED, irene.delgado@uneatlantico.es, kilian.tutusaus@uneatlantico.es, UNSPECIFIED, UNSPECIFIED (2026) Benchmarking multiple instance learning architectures from patches to pathology for prostate cancer detection and grading using attention-based weak supervision. Scientific Reports. ISSN 2045-2322

Article Subjects > Nutrition Europe University of Atlantic > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Articles and Books
Universidad Internacional do Cuanza > Research > Scientific Production
University of La Romana > Research > Scientific Production Open English Background/Objectives: The growing integration of Artificial Intelligence (AI) and chatbots in health professional education offers innovative methods to enhance learning and clinical preparedness. This study aimed to evaluate the educational impact and perceptions in university students of Human Nutrition and Dietetics, regarding the utility, usability, and design of the E+DIEting_Lab chatbot platform when implemented in clinical nutrition training. Methods: The platform was piloted from December 2023 to April 2025 involving 475 students from multiple European universities. While all 475 students completed the initial survey, 305 finished the follow-up evaluation, representing a 36% attrition rate. Participants completed surveys before and after interacting with the chatbots, assessing prior experience, knowledge, skills, and attitudes. Data were analyzed using descriptive statistics and independent samples t-tests to compare pre- and post-intervention perceptions. Results: A total of 475 university students completed the initial survey and 305 the final evaluation. Most university students were females (75.4%), with representation from six languages and diverse institutions. Students reported clear perceived learning gains: 79.7% reported updated practical skills in clinical dietetics and communication were updated, 90% felt that new digital tools improved classroom practice, and 73.9% reported enhanced interpersonal skills. Self-rated competence in using chatbots as learning tools increased significantly, with mean knowledge scores rising from 2.32 to 2.66 and skills from 2.39 to 2.79 on a 0–5 Likert scale (p < 0.001 for both). Perceived effectiveness and usefulness of chatbots as self-learning tools remained positive but showed a small decline after use (effectiveness from 3.63 to 3.42; usefulness from 3.63 to 3.45), suggesting that hands-on experience refined, but did not diminish, students’ overall favorable views of the platform. Conclusions: The implementation and pilot evaluation of the E+DIEting_Lab self-learning virtual patient chatbot platform demonstrate that structured digital simulation tools can significantly improve perceived clinical nutrition competences. These findings support chatbot adoption in dietetics curricula and inform future digital education innovations. metadata Elío Pascual, Iñaki; Tutusaus, Kilian; Eguren García, Imanol; Lasarte García, Álvaro; Ortega-Mansilla, Arturo; Prola, Thomas and Sumalla Cano, Sandra mail inaki.elio@uneatlantico.es, kilian.tutusaus@uneatlantico.es, imanol.eguren@uneatlantico.es, UNSPECIFIED, arturo.ortega@uneatlantico.es, thomas.prola@uneatlantico.es, sandra.sumalla@uneatlantico.es (2026) Innovative Application of Chatbots in Clinical Nutrition Education: The E+DIEting_Lab Experience in University Students. Nutrients, 18 (2). p. 257. ISSN 2072-6643

Article Subjects > Engineering Europe University of Atlantic > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Articles and Books
Universidad Internacional do Cuanza > Research > Scientific Production
University of La Romana > Research > Scientific Production Open English In the rapidly evolving landscape of artificial intelligence (AI) and the Internet of Things (IoT), the significance of device diagnostics and prognostics is paramount for guaranteeing the dependable operation and upkeep of intricate systems. The capacity to precisely diagnose and preemptively predict potential failures holds the potential to considerably amplify maintenance efficiency, diminish downtime, and optimize resource allocation. The wealth of information offered by telemetry data gathered from IoT devices presents an opportunity for diagnostics and prognostics applications. However, extracting valuable insights and making well-timed decisions from this extensive data reservoir remains a formidable challenge. This study proposes a novel AI-driven framework that integrates forward chaining and backward chaining algorithms to analyze telemetry data from IoT devices. The proposed methodology utilizes rule-based inference to detect real-time anomalies and predict potential future failures, providing a dual-layered approach for diagnostics and prognostics. The results show that the diagnostics engine using forward chaining detects real-time issues like “High Temperature” and “Low Pressure,” while the prognostics engine with backward chaining predicts potential future occurrences of these issues, enabling proactive prevention measures. The experimental results demonstrate that adopting this approach could offer valuable assistance to authorities and stakeholders. Accurate early diagnosis and prediction of potential failures have the capability to greatly improve maintenance efficiency, minimize downtime, and optimize cost. metadata Farooq, Muhammad Shoaib; Mir, Rizwan Pervez; Alvi, Atif; Tutusaus, Kilian; García Villena, Eduardo; Alrowais, Fadwa; Karamti, Hanen and Ashraf, Imran mail UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, kilian.tutusaus@uneatlantico.es, eduardo.garcia@uneatlantico.es, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED (2025) Harnessing AI forward and backward chaining with telemetry data for enhanced diagnostics and prognostics of smart devices. Scientific Reports, 15 (1). ISSN 2045-2322

Article Subjects > Biomedicine
Subjects > Engineering
Subjects > Nutrition Europe University of Atlantic > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Articles and Books
Universidad Internacional do Cuanza > Research > Scientific Production Closed English Obesity and overweight has increased in the last year and has become a pandemic disease, the result of sedentary lifestyles and unhealthy diets rich in sugars, refined starches, fats and calories. Machine learning (ML) has proven to be very useful in the scientific community, especially in the health sector. With the aim of providing useful tools to help nutritionists and dieticians, research focused on the development of ML and Deep Learning (DL) algorithms and models is searched in the literature. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol has been used, a very common technique applied to carry out revisions. In our proposal, 17 articles have been filtered in which ML and DL are applied in the prediction of diseases, in the delineation of treatment strategies, in the improvement of personalized nutrition and more. Despite expecting better results with the use of DL, according to the selected investigations, the traditional methods are still the most used and the yields in both cases fluctuate around positive values, conditioned by the databases (transformed in each case) to a greater extent than by the artificial intelligence paradigm used. Conclusions: An important compilation is provided for the literature in this area. ML models are time-consuming to clean data, but (like DL) they allow automatic modeling of large volumes of data which makes them superior to traditional statistics. metadata Ferreras, Antonio; Sumalla Cano, Sandra; Martínez-Licort, Rosmeri; Elío Pascual, Iñaki; Tutusaus, Kilian; Prola, Thomas; Vidal Mazón, Juan Luis; Sahelices, Benjamín and de la Torre Díez, Isabel mail UNSPECIFIED, sandra.sumalla@uneatlantico.es, UNSPECIFIED, inaki.elio@uneatlantico.es, kilian.tutusaus@uneatlantico.es, thomas.prola@uneatlantico.es, juanluis.vidal@uneatlantico.es, UNSPECIFIED, UNSPECIFIED (2023) Systematic Review of Machine Learning applied to the Prediction of Obesity and Overweight. Journal of Medical Systems, 47 (1). ISSN 1573-689X

Article Subjects > Biomedicine
Subjects > Engineering Europe University of Atlantic > Research > Scientific Production
Fundación Universitaria Internacional de Colombia > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Articles and Books
Universidad Internacional do Cuanza > Research > Scientific Production Open English The diagnosis of early-stage lung cancer is challenging due to its asymptomatic nature, especially given the repeated radiation exposure and high cost of computed tomography(CT). Examining the lung CT images to detect pulmonary nodules, especially the cell lung cancer lesions, is also tedious and prone to errors even by a specialist. This study proposes a cancer diagnostic model based on a deep learning-enabled support vector machine (SVM). The proposed computer-aided design (CAD) model identifies the physiological and pathological changes in the soft tissues of the cross-section in lung cancer lesions. The model is first trained to recognize lung cancer by measuring and comparing the selected profile values in CT images obtained from patients and control patients at their diagnosis. Then, the model is tested and validated using the CT scans of both patients and control patients that are not shown in the training phase. The study investigates 888 annotated CT scans from the publicly available LIDC/IDRI database. The proposed deep learning-assisted SVM-based model yields 94% accuracy for pulmonary nodule detection representing early-stage lung cancer. It is found superior to other existing methods including complex deep learning, simple machine learning, and the hybrid techniques used on lung CT images for nodule detection. Experimental results demonstrate that the proposed approach can greatly assist radiologists in detecting early lung cancer and facilitating the timely management of patients. metadata Shafi, Imran; Din, Sadia; Khan, Asim; Díez, Isabel De La Torre; Pali-Casanova, Ramón; Tutusaus, Kilian and Ashraf, Imran mail UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, ramon.pali@unini.edu.mx, kilian.tutusaus@uneatlantico.es, UNSPECIFIED (2022) An Effective Method for Lung Cancer Diagnosis from CT Scan Using Deep Learning-Based Support Vector Network. Cancers, 14 (21). p. 5457. ISSN 2072-6694

Article Subjects > Engineering Europe University of Atlantic > Research > Scientific Production
Fundación Universitaria Internacional de Colombia > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Articles and Books
Universidad Internacional do Cuanza > Research > Scientific Production Open English The purpose of this article is to help to bridge the gap between sustainability and its application to project management by developing a methodology based on artificial intelligence to diagnose, classify, and forecast the level of sustainability of a sample of 186 projects aimed at local communities in Latin American and Caribbean countries. First, the compliance evaluation with the Sustainable Development Goals (SDGs) within the framework of the 2030 Agenda served to diagnose and determine, through fuzzy sets, a global sustainability index for the sample, resulting in a value of 0.638, in accordance with the overall average for the region. Probabilistic predictions were then made on the sustainability of the projects using a series of supervised learning classifiers (SVM, Random Forest, AdaBoost, KNN, etc.), with the SMOTE resampling technique, which provided a significant improvement toward the results of the different metrics of the base models. In this context, the Support Vector Machine (SVM) + SMOTE was the best classification algorithm, with accuracy of 0.92. Lastly, the extrapolation of this methodology is to be expected toward other realities and local circumstances, contributing to the fulfillment of the SDGs and the development of individual and collective capacities through the management and direction of projects. metadata García Villena, Eduardo; Pascual Barrera, Alina Eugenia; Álvarez, Roberto Marcelo; Dzul López, Luis Alonso; Tutusaus, Kilian; Vidal Mazón, Juan Luis; Miró Vera, Yini Airet; Brie, Santiago and López Flores, Miguel A. mail eduardo.garcia@uneatlantico.es, alina.pascual@unini.edu.mx, roberto.alvarez@uneatlantico.es, luis.dzul@uneatlantico.es, kilian.tutusaus@uneatlantico.es, juanluis.vidal@uneatlantico.es, yini.miro@uneatlantico.es, santiago.brie@uneatlantico.es, miguelangel.lopez@uneatlantico.es (2022) Evaluation of the Sustainable Development Goals in the Diagnosis and Prediction of the Sustainability of Projects Aimed at Local Communities in Latin America and the Caribbean. Applied Sciences, 12 (21). p. 11188. ISSN 2076-3417

Article Subjects > Engineering Europe University of Atlantic > Research > Scientific Production
Fundación Universitaria Internacional de Colombia > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Articles and Books
Universidad Internacional do Cuanza > Research > Scientific Production Open English β-Thalassemia is one of the dangerous causes of the high mortality rate in the Mediterranean countries. Substantial resources are required to save a β-Thalassemia carriers’ life and early detection of thalassemia patients can help appropriate treatment to increase the carrier’s life expectancy. Being a genetic disease, it can not be prevented however the analysis of several indicators in parents’ blood can be used to detect disorders causing Thalassemia. Laboratory tests for Thalassemia are time-consuming and expensive like high-performance liquid chromatography, Complete Blood Count (CBC) with peripheral smear, genetic test, etc. Red blood indices from CBC can be used with machine learning models for the same task. Despite the available approaches for Thalassemia carriers from CBC data, gaps exist between the desired and achieved accuracy. Moreover, the data imbalance problem is studied well which makes the models less generalizable. This study proposes a highly accurate approach for β-Thalassemia detection using red blood indices from CBC augmented by supervised machine learning. In view of the fact that all the features do not carry predictive information regarding the target variable, this study employs a unified framework of two features selection techniques including Principal Component Analysis (PCA) and Singular Vector Decomposition (SVD). The data imbalance between β-Thalassemia carrier and non-carriers is handled by Synthetic Minority Oversampling Technique (SMOTE) and Adaptive Synthetic (ADASYN). Extensive experiments are performed using many state-of-the-art machine learning models and deep learning models. Experimental results indicate the superiority of the proposed approach over existing approaches with an accuracy score of 0.96. metadata Rustam, Furqan; Ashraf, Imran; Jabbar, Shehbaz; Tutusaus, Kilian; Mazas Pérez-Oleaga, Cristina; Pascual Barrera, Alina Eugenia and de la Torre Diez, Isabel mail UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, kilian.tutusaus@uneatlantico.es, cristina.mazas@uneatlantico.es, alina.pascual@unini.edu.mx, UNSPECIFIED (2022) Prediction β-Thalassemia carriers using complete blood count features. Scientific Reports, 12 (1). ISSN 2045-2322

Article Subjects > Education Europe University of Atlantic > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Articles and Books
Universidad Internacional do Cuanza > Research > Scientific Production Open English The purpose of this article was to evaluate the level of satisfaction of a sample of graduates in relation to different online postgraduate programs in the environmental area, as part of the process of continuous improvement in which the educational institution was immersed for the renewal of its accreditation before the corresponding official bodies. Based on the bibliographic review of a series of models and tools, a Likert scale measurement instrument was developed. This instrument, once applied and validated, showed a good level of reliability, with more than three quarters of the participants having a positive evaluation of satisfaction. Likewise, to facilitate the relational study, and after confirming the suitability of performing a factor analysis, four variable grouping factors were determined, which explained a good part of the variability of the instrument’s items. As a result of the analysis, it was found that there were significant values of low satisfaction in graduates from the Eurasian area, mainly in terms of organizational issues and academic expectations. On the other hand, it was observed that the methodological aspects of the “Auditing” and “Biodiversity” programs showed higher levels of dissatisfaction than the rest, with no statistically significant relationships between gender, entry profile or age groups. The methodology followed and the rigor in determining the validity and reliability of the instrument, as well as the subsequent analysis of the results, endorsed by the review of the documented information, suggest that the instrument can be applied to other multidisciplinary programs for decision making with guarantees in the educational field metadata García Villena, Eduardo; Pueyo Villa, Silvia; Delgado Noya, Irene; Tutusaus, Kilian; Ruiz Salces, Roberto and Pascual Barrera, Alina Eugenia mail eduardo.garcia@uneatlantico.es, silvia.pueyo@uneatlantico.es, irene.delgado@uneatlantico.es, kilian.tutusaus@uneatlantico.es, roberto.ruiz@uneatlantico.es, alina.pascual@unini.edu.mx (2021) Instrumentalization of a Model for the Evaluation of the Level of Satisfaction of Graduates under an E-Learning Methodology: A Case Analysis Oriented to Postgraduate Studies in the Environmental Field. Sustainability, 13 (9). p. 5112. ISSN 2071-1050