Items where Author is "Pascual Barrera, Alina Eugenia"

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Number of documents: 8.

Article Subjects > Nutrition Europe University of Atlantic > Research > Scientific Production
Fundación Universitaria Internacional de Colombia > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Articles and Books Open English Alpha-linolenic acid (ALA) is a long-chain polyunsaturated essential fatty acid of the Ω3 series found mainly in vegetables, especially in the fatty part of oilseeds, dried fruit, berries, and legumes. It is very popular for its preventive use in several diseases: It seems to reduce the risk of the onset or decrease some phenomena related to inflammation, oxidative stress, and conditions of dysregulation of the immune response. Recent studies have confirmed these unhealthy situations also in patients with severe coronavirus disease 2019 (COVID-19). Different findings (in vitro, in vivo, and clinical ones), summarized and analyzed in this review, have showed an important role of ALA in other various non-COVID physiological and pathological situations against “cytokines storm,” chemokines secretion, oxidative stress, and dysregulation of immune cells that are also involved in the infection of the 2019 novel coronavirus. According to the effects of ALA against all the aforementioned situations (also present in patients with a severe clinical picture of severe acute respiratory syndrome-(CoV-2) infection), there may be the biologic plausibility of a prophylactic effect of this compound against COVID-19 symptoms and fatality. metadata Cianciosi, Danila; Diaz, Yasmany Armas; Gaddi, Antonio Vittorino; Capello, Fabio; Savo, Maria Teresa; Pali-Casanova, Ramón; Martínez Espinosa, Julio César; Pascual Barrera, Alina Eugenia; Navarro‐Hortal, Maria‐Dolores; Tian, Lingmin; Bai, Weibin; Giampieri, Francesca and Battino, Maurizio mail UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, ramon.pali@unini.edu.mx, ulio.martinez@unini.edu.mx, alina.pascual@unini.edu.mx, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, francesca.giampieri@uneatlantico.es, UNSPECIFIED (2023) Can alpha‐linolenic acid be a modulator of “cytokine storm,” oxidative stress and immune response in SARS‐CoV‐2 infection? Food Frontiers. ISSN 2643-8429

Article Subjects > Engineering Europe University of Atlantic > Research > Scientific Production
Fundación Universitaria Internacional de Colombia > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Articles and Books
Universidad Internacional do Cuanza > Research > Scientific Production Open English The demand for cloud computing has drastically increased recently, but this paradigm has several issues due to its inherent complications, such as non-reliability, latency, lesser mobility support, and location-aware services. Fog computing can resolve these issues to some extent, yet it is still in its infancy. Despite several existing works, these works lack fault-tolerant fog computing, which necessitates further research. Fault tolerance enables the performing and provisioning of services despite failures and maintains anti-fragility and resiliency. Fog computing is highly diverse in terms of failures as compared to cloud computing and requires wide research and investigation. From this perspective, this study primarily focuses on the provision of uninterrupted services through fog computing. A framework has been designed to provide uninterrupted services while maintaining resiliency. The geographical information system (GIS) services have been deployed as a test bed which requires high computation, requires intensive resources in terms of CPU and memory, and requires low latency. Keeping different types of failures at different levels and their impacts on service failure and greater response time in mind, the framework was made anti-fragile and resilient at different levels. Experimental results indicate that during service interruption, the user state remains unaffected. metadata Mir, Tahira Sarwar; Liaqat, Hannan Bin; Kiren, Tayybah; Sana, Muhammad Usman; Álvarez, Roberto Marcelo; Miró Vera, Yini Airet; Pascual Barrera, Alina Eugenia and Ashraf, Imran mail UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, roberto.alvarez@uneatlantico.es, yini.miro@uneatlantico.es, alina.pascual@unini.edu.mx, UNSPECIFIED (2022) Antifragile and Resilient Geographical Information System Service Delivery in Fog Computing. Sensors, 22 (22). p. 8778. ISSN 1424-8220

Article Subjects > Engineering Europe University of Atlantic > Research > Scientific Production
Fundación Universitaria Internacional de Colombia > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Articles and Books
Universidad Internacional do Cuanza > Research > Scientific Production Open English The purpose of this article is to help to bridge the gap between sustainability and its application to project management by developing a methodology based on artificial intelligence to diagnose, classify, and forecast the level of sustainability of a sample of 186 projects aimed at local communities in Latin American and Caribbean countries. First, the compliance evaluation with the Sustainable Development Goals (SDGs) within the framework of the 2030 Agenda served to diagnose and determine, through fuzzy sets, a global sustainability index for the sample, resulting in a value of 0.638, in accordance with the overall average for the region. Probabilistic predictions were then made on the sustainability of the projects using a series of supervised learning classifiers (SVM, Random Forest, AdaBoost, KNN, etc.), with the SMOTE resampling technique, which provided a significant improvement toward the results of the different metrics of the base models. In this context, the Support Vector Machine (SVM) + SMOTE was the best classification algorithm, with accuracy of 0.92. Lastly, the extrapolation of this methodology is to be expected toward other realities and local circumstances, contributing to the fulfillment of the SDGs and the development of individual and collective capacities through the management and direction of projects. metadata García Villena, Eduardo; Pascual Barrera, Alina Eugenia; Álvarez, Roberto Marcelo; Dzul López, Luis Alonso; Tutusaus, Kilian; Vidal Mazón, Juan Luis; Miró Vera, Yini Airet; Brie, Santiago and López Flores, Miguel A. mail eduardo.garcia@uneatlantico.es, alina.pascual@unini.edu.mx, roberto.alvarez@uneatlantico.es, luis.dzul@uneatlantico.es, kilian.tutusaus@uneatlantico.es, juanluis.vidal@uneatlantico.es, yini.miro@uneatlantico.es, santiago.brie@uneatlantico.es, miguelangel.lopez@uneatlantico.es (2022) Evaluation of the Sustainable Development Goals in the Diagnosis and Prediction of the Sustainability of Projects Aimed at Local Communities in Latin America and the Caribbean. Applied Sciences, 12 (21). p. 11188. ISSN 2076-3417

Article Subjects > Biomedicine
Subjects > Engineering Europe University of Atlantic > Research > Scientific Production
Fundación Universitaria Internacional de Colombia > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Articles and Books
Universidad Internacional do Cuanza > Research > Scientific Production Open English Mobility and low energy consumption are considered the main requirements for wireless body area sensor networks (WBASN) used in healthcare monitoring systems (HMS). In HMS, battery-powered sensor nodes with limited energy are used to obtain vital statistics about the body. Hence, energy-efficient schemes are desired to maintain long-term and steady connectivity of the sensor nodes. A sheer amount of energy is consumed in activities such as idle listening, excessive transmission and reception of control messages, packet collisions and retransmission of packets, and poor path selection, that may lead to more energy consumption. A combination of adaptive scheduling with an energy-efficient protocol can help select an appropriate path at a suitable time to minimize the control overhead, energy consumption, packet collision, and excessive idle listening. This paper proposes a region-based energy-efficient multipath routing (REMR) approach that divides the entire sensor network into clusters with preferably multiple candidates to represent each cluster. The cluster representatives (CRs) route packets through various clusters. For routing, the energy requirement of each route is considered, and the path with minimum energy requirements is selected. Similarly, end-to-end delay, higher throughput, and packet-delivery ratio are considered for packet routing. metadata Akbar, Shuja; Mehdi, Muhammad Mohsin; Jamal, M. Hasan; Raza, Imran; Hussain, Syed Asad; Breñosa, Jose; Martínez Espinosa, Julio César; Pascual Barrera, Alina Eugenia and Ashraf, Imran mail UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, josemanuel.brenosa@uneatlantico.es, ulio.martinez@unini.edu.mx, alina.pascual@unini.edu.mx, UNSPECIFIED (2022) Multipath Routing in Wireless Body Area Sensor Network for Healthcare Monitoring. Healthcare, 10 (11). p. 2297. ISSN 2227-9032

Article Subjects > Engineering Europe University of Atlantic > Research > Scientific Production
Fundación Universitaria Internacional de Colombia > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Articles and Books
Universidad Internacional do Cuanza > Research > Scientific Production Open English β-Thalassemia is one of the dangerous causes of the high mortality rate in the Mediterranean countries. Substantial resources are required to save a β-Thalassemia carriers’ life and early detection of thalassemia patients can help appropriate treatment to increase the carrier’s life expectancy. Being a genetic disease, it can not be prevented however the analysis of several indicators in parents’ blood can be used to detect disorders causing Thalassemia. Laboratory tests for Thalassemia are time-consuming and expensive like high-performance liquid chromatography, Complete Blood Count (CBC) with peripheral smear, genetic test, etc. Red blood indices from CBC can be used with machine learning models for the same task. Despite the available approaches for Thalassemia carriers from CBC data, gaps exist between the desired and achieved accuracy. Moreover, the data imbalance problem is studied well which makes the models less generalizable. This study proposes a highly accurate approach for β-Thalassemia detection using red blood indices from CBC augmented by supervised machine learning. In view of the fact that all the features do not carry predictive information regarding the target variable, this study employs a unified framework of two features selection techniques including Principal Component Analysis (PCA) and Singular Vector Decomposition (SVD). The data imbalance between β-Thalassemia carrier and non-carriers is handled by Synthetic Minority Oversampling Technique (SMOTE) and Adaptive Synthetic (ADASYN). Extensive experiments are performed using many state-of-the-art machine learning models and deep learning models. Experimental results indicate the superiority of the proposed approach over existing approaches with an accuracy score of 0.96. metadata Rustam, Furqan; Ashraf, Imran; Jabbar, Shehbaz; Tutusaus, Kilian; Mazas Pérez-Oleaga, Cristina; Pascual Barrera, Alina Eugenia and de la Torre Diez, Isabel mail UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, kilian.tutusaus@uneatlantico.es, cristina.mazas@uneatlantico.es, alina.pascual@unini.edu.mx, UNSPECIFIED (2022) Prediction β-Thalassemia carriers using complete blood count features. Scientific Reports, 12 (1). ISSN 2045-2322

Article Subjects > Education Europe University of Atlantic > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Articles and Books
Universidad Internacional do Cuanza > Research > Scientific Production Open English The purpose of this article was to evaluate the level of satisfaction of a sample of graduates in relation to different online postgraduate programs in the environmental area, as part of the process of continuous improvement in which the educational institution was immersed for the renewal of its accreditation before the corresponding official bodies. Based on the bibliographic review of a series of models and tools, a Likert scale measurement instrument was developed. This instrument, once applied and validated, showed a good level of reliability, with more than three quarters of the participants having a positive evaluation of satisfaction. Likewise, to facilitate the relational study, and after confirming the suitability of performing a factor analysis, four variable grouping factors were determined, which explained a good part of the variability of the instrument’s items. As a result of the analysis, it was found that there were significant values of low satisfaction in graduates from the Eurasian area, mainly in terms of organizational issues and academic expectations. On the other hand, it was observed that the methodological aspects of the “Auditing” and “Biodiversity” programs showed higher levels of dissatisfaction than the rest, with no statistically significant relationships between gender, entry profile or age groups. The methodology followed and the rigor in determining the validity and reliability of the instrument, as well as the subsequent analysis of the results, endorsed by the review of the documented information, suggest that the instrument can be applied to other multidisciplinary programs for decision making with guarantees in the educational field metadata García Villena, Eduardo; Pueyo Villa, Silvia; Delgado Noya, Irene; Tutusaus, Kilian; Ruiz Salces, Roberto and Pascual Barrera, Alina Eugenia mail eduardo.garcia@uneatlantico.es, silvia.pueyo@uneatlantico.es, irene.delgado@uneatlantico.es, kilian.tutusaus@uneatlantico.es, roberto.ruiz@uneatlantico.es, alina.pascual@unini.edu.mx (2021) Instrumentalization of a Model for the Evaluation of the Level of Satisfaction of Graduates under an E-Learning Methodology: A Case Analysis Oriented to Postgraduate Studies in the Environmental Field. Sustainability, 13 (9). p. 5112. ISSN 2071-1050

Article Subjects > Nutrition Ibero-american International University > Research > Articles and Books Open Spanish En la presente investigación, se evaluó la presencia de E. coli, hongos y levaduras en la harina proveniente de las cascarillas de las variedades de cacao Nacional Arriba y el cacao CCN51 en Ecuador, para su uso en los procesos de elaboración de galletas, panes y pasteles. Se tomaron cinco muestras de 2000 g cada una, de 5 lotes diferentes para cada variedad de cacao en dos industrias cacaoteras en la provincia del Guayas. Se realizó la molienda con un molino marca Oster, se homogenizaron las muestras y se empacaron 500 g de las cáscaras molidas de cada variedad en fundas de polietileno de baja densidad, para poder realizar los análisis microbiológicos. Las muestras fueron enviadas a un laboratorio certificado para realizar los análisis correspondientes. Debido a que no existe alguna norma de calidad para la harina proveniente de cascarillas de cacao en Ecuador, se aplicaron las normas INEN 616 e INEN 621, las cuales definen los requisitos que debe cumplir la harina de trigo y los chocolates respetivamente para que sea apta para el consumo humano, comprobando que la harina proveniente de las cascarillas de ambas variedades cumple con los criterios establecidos en estas normas. metadata El Salous, Ahmed and Pascual Barrera, Alina Eugenia mail UNSPECIFIED, alina.pascual@unini.edu.mx (2018) Determinación de e. Coli, hongos y levaduras en la harina proveniente de las cascarillas de dos variedades de cacao en Ecuador. Revista Universidad y Sociedad, 10 (1). pp. 164-167.

Generated on Sat Apr 4 23:45:34 2026 UTC.

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Benchmarking multiple instance learning architectures from patches to pathology for prostate cancer detection and grading using attention-based weak supervision

Histopathological evaluation is necessary for the diagnosis and grading of prostate cancer, which is still one of the most common cancers in men globally. Traditional evaluation is time-consuming, prone to inter-observer variability, and challenging to scale. The clinical usefulness of current AI systems is limited by the need for comprehensive pixel-level annotations. The objective of this research is to develop and evaluate a large-scale benchmarking study on a weakly supervised deep learning framework that minimizes the need for annotation and ensures interpretability for automated prostate cancer diagnosis and International Society of Urological Pathology (ISUP) grading using whole slide images (WSIs). This study rigorously tested six cutting-edge multiple instance learning (MIL) architectures (CLAM-MB, CLAM-SB, ILRA-MIL, AC-MIL, AMD-MIL, WiKG-MIL), three feature encoders (ResNet50, CTransPath, UNI2), and four patch extraction techniques (varying sizes and overlap) using the PANDA dataset (10,616 WSIs), yielding 72 experimental configurations. The methodology used distributed cloud computing to process over 31 million tissue patches, implementing advanced attention mechanisms to ensure clinical interpretability through Grad-CAM visualizations. The optimum configuration (UNI2 encoder with ILRA-MIL, 256 256 patches, 50% overlap) achieved 78.75% accuracy and 90.12% quadratic weighted kappa (QWK), outperforming traditional methods and approaching expert pathologist-level diagnostic capability. Overlapping smaller patches offered the best balance of spatial resolution and contextual information, while domain-specific foundation models performed noticeably better than generic encoders. This work is the first large-scale, comprehensive comparison of weekly supervised MIL methods for prostate cancer diagnosis and grading. The proposed approach has excellent clinical diagnostic performance, scalability, practical feasibility through cloud computing, and interpretability using visualization tools.

Producción Científica

Naveed Anwer Butt mail , Dilawaiz Sarwat mail , Irene Delgado Noya mail irene.delgado@uneatlantico.es, Kilian Tutusaus mail kilian.tutusaus@uneatlantico.es, Nagwan Abdel Samee mail , Imran Ashraf mail ,

Butt

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A Systematic Literature Review on Integrated Deep Learning and Multi-Agent Vision-Language Frameworks for Pathology Image Analysis and Report Generation

This systematic literature review (SLR) investigates the integration of deep learning (DL), vision-language models(VLMs), and multi-agent systems in the analysis of pathology images and automated report generation. The rapidadvancement of whole-slide imaging (WSI) technologies has posed new challenges in pathology, especially due to thescale and complexity of the data. DL techniques in general and convolutional neural networks (CNNs) and transform-ers in particular have signiﬁcantly enhanced image analysis tasks including segmentation, classiﬁcation, and detection.However, these models often lack generalizability to generate coherent, clinically relevant text, thus necessitating theintegration of VLMs and large language models (LLMs). This review examines the eﬀectiveness of VLMs and LLMsin bridging the gap between visual data and clinical text, focusing on their potential for automating the generationof pathology reports. Additionally, multi-agent systems, which leverage specialized artiﬁcial intelligence (AI) agentsto collaboratively perform diagnostic tasks, are explored for their contributions to improving diagnostic accuracy andscalability. Through a synthesis of recent studies, this review highlights the successes, challenges, and future direc-tions of these AI technologies in pathology diagnostics, oﬀering a comprehensive foundation for the development ofintegrated, AI-driven diagnostic workﬂows.

Producción Científica

Usama Ali mail , Imran Shafi mail , Jamil Ahmad mail , Arlette Zárate Cáceres mail , Thania Chio Montero mail , Hafiz Muhammad Raza ur Rehman mail , Imran Ashraf mail ,

Ali

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Fish consumption and cognitive function in aging: a systematic review of observational studies

Epidemiological studies consistently link higher fish intake with slower rates of cognitive decline and lower dementia incidence. The aim of the present study was to systematically review existing observational studies investigating the association between fish consumption and cognitive function in older adults. A total of 25 studies (8 cross-sectional and 17 prospective including mainly healthy older adults, age range of participants ranging from 18 to 30 years at baseline in prospective studies to 65 to 91 years, representing the upper limit of the age spectrum) were reviewed. Cognitive functions currently investigated in most published studies included various domains, such as global cognition, memory (episodic, working), executive function (planning, inhibition, flexibility), attention and processing speed. Existing studies greatly vary in terms of design (cross-sectional and prospective), geographical area, number of participants involved, and tools used to assess the outcomes of interest. The main findings across studies are not univocal, with some studies reporting stronger evidence of association between fish consumption and various cognitive domains, while others addressed rather null findings. The most consistently responsive domains were processing speed, executive functioning, semantic memory, and global cognitive ability among individuals consuming fish at least weekly, which are highly relevant to both neurodegenerative and vascular forms of cognitive impairment. Positive associations were also observed for verbal memory and general memory, though these were less uniform and often attenuated after multivariable adjustment. In contrast, associations with reaction time, verbal-numerical reasoning, and broad composite scores were inconsistent, and several fully adjusted models showed null results. In conclusion, the evidence suggests that regular fish intake (typically ≥1–2 servings per week) is linked to preserved cognitive performance, although some inconsistent findings require further investigations.

Producción Científica

Justyna Godos mail , Giuseppe Caruso mail , Agnieszka Micek mail , Alberto Dolci mail , Carmen Lilí Rodríguez Velasco mail carmen.rodriguez@uneatlantico.es, Evelyn Frias-Toral mail , Jason Di Giorgio mail , Nicola Veronese mail , Andrea Lehoczki mail , Mario Siervo mail , Zoltan Ungvari mail , Giuseppe Grosso mail ,

Godos

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A scalable and secure federated learning authentication scheme for IoT

Secure and scalable authentication remains a fundamental challenge in Internet of Things (IoT) networks due to constrained device resources, dynamic topology, and the absence of centralized trust infrastructures. Conventional password-based and certificate-driven authentication schemes incur high computation, storage, and communication overhead, limiting their suitability for large-scale deployments. To address these limitations, this paper proposes ScLBS, a federated learning (FL)–based self-certified authentication scheme for distributed and sustainable IoT environments. ScLBS integrates self-certified public key cryptography with FL-driven trust adaptation, enabling decentralized public key derivation without reliance on third-party certificate authorities or exposure of private credentials. A zero-knowledge mechanism combined with location-aware authentication strengthens resistance to impersonation, Sybil, and replay attacks. Hierarchical key management supported by a -tree enables efficient group rekeying and preserves forward and backward secrecy under dynamic membership. Formal security verification is conducted under the Dolev–Yao adversary model using ProVerif, confirming secrecy of private and session keys (SKs) and correctness of authentication. Extensive NS-3 simulations and ablation analysis demonstrate that ScLBS achieves lower authentication delay, reduced message overhead, improved network utilization, and decreased energy consumption compared to representative IoT authentication schemes, while maintaining bounded FL overhead. These results indicate that ScLBS provides a balanced trade-off between security strength, scalability, and resource efficiency for constrained IoT networks.

Producción Científica

Premkumar Chithaluru mail , B. Veera Jyothi mail , Fahd S. Alharithi mail , Wojciech Ksiazek mail , M. Ramchander mail , Aman Singh mail aman.singh@uneatlantico.es, Ravi Kumar Rachavaram mail ,

Chithaluru

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Human Activity Recognition in Domestic Settings Based on Optical Techniques and Ensemble Models

Human activity recognition (HAR) is essential in many applications, such as smart homes, assisted living, healthcare monitoring, rehabilitation, physiotherapy, and geriatric care. Conventional methods of HAR use wearable sensors, e.g., acceleration sensors and gyroscopes. However, they are limited by issues such as sensitivity to position, user inconvenience, and potential health risks with long-term use. Optical camera systems that are vision-based provide an alternative that is not intrusive; however, they are susceptible to variations in lighting, intrusions, and privacy issues. The paper uses an optical method of recognizing human domestic activities based on pose estimation and deep learning ensemble models. The skeletal keypoint features proposed in the current methodology are extracted from video data using PoseNet to generate a privacy-preserving representation that captures key motion dynamics without being sensitive to changes in appearance. A total of 30 subjects (15 male and 15 female) were sampled across 2734 activity samples, including nine daily domestic activities. There were six deep learning architectures, namely, the Transformer (Transformer), Long Short-Term Memory (LSTM), Gated Recurrent Unit (GRU), Multilayer Perceptron (MLP), One-Dimensional Convolutional Neural Network (1D CNN), and a hybrid Convolutional Neural Network–Long Short-Term Memory (CNN–LSTM) architecture. The results on the hold-out test set show that the CNN–LSTM architecture achieves an accuracy of 98.78% within our experimental setting. Leave-One-Subject-Out cross-validation further confirms robust generalization across unseen individuals, with CNN–LSTM achieving a mean accuracy of 97.21% ± 1.84% across 30 subjects. The results demonstrate that vision-based pose estimation with deep learning is a useful, precise, and non-intrusive approach to HAR in smart healthcare and home automation systems.

Producción Científica

Muhammad Amjad Raza mail , Nasir Mehmood mail , Hafeez Ur Rehman Siddiqui mail , Adil Ali Saleem mail , Roberto Marcelo Álvarez mail roberto.alvarez@uneatlantico.es, Yini Airet Miró Vera mail yini.miro@uneatlantico.es, Isabel de la Torre Díez mail ,

Raza

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