Items where Author is "Gracia Villar, Santos"
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Article
Article
Subjects > Engineering
Europe University of Atlantic > Research > Scientific Production
Fundación Universitaria Internacional de Colombia > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Articles and Books
Universidad Internacional do Cuanza > Research > Scientific Production
University of La Romana > Research > Scientific Production
Open
English
New energy vehicles (NEVs) has emerged as a sustainable alternative to conventional vehicles, however have unresolved reliability challenges due to their complex electronic systems and varying operating conditions. Faults in drivetrain and battery systems, occurring at rates up to 12% annually, present significant barriers to the widespread adoption of NEVs. This study proposes a robust fault detection framework that applies multiple machine learning and deep learning models to address these challenges. The research utilizes the benchmark NEV fault diagnosis dataset, which contains real-world sensor data from NEVs. The models tested include logistic regression, passive-aggressive classifier, ridge classifier, perceptron, gated recurrent unit (GRU), convolutional neural network, and artificial neural network. The proposed ensemble GRULogX model stands out among the implemented model, leveraging GRU with logistic regression and other key classifiers, and achieved 99% accuracy, demonstrating high precision and recall. Cross-validation and hyperparameter optimization were adopted to further ensure the model’s generalizability and reliability. This research enhances the fault detection capabilities of NEVs, thereby improving their reliability and supporting the wider adoption of clean energy transportation solutions.
metadata
Akhtar, Iqra; Nabeel, Mahnoor; Shahid, Umair; Munir, Kashif; Raza, Ali; Delgado Noya, Irene; Gracia Villar, Santos and Ashraf, Imran
mail
UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, irene.delgado@uneatlantico.es, santos.gracia@uneatlantico.es, UNSPECIFIED
(2026)
Enhancing fault detection in new energy vehicles via novel ensemble approach.
Scientific Reports, 16 (1).
ISSN 2045-2322
Article
Subjects > Biomedicine
Europe University of Atlantic > Research > Scientific Production
Fundación Universitaria Internacional de Colombia > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Articles and Books
Universidad Internacional do Cuanza > Research > Scientific Production
University of La Romana > Research > Scientific Production
Open
English
Background
Nowadays, there is no correlation between levels of cortisol and pain in the prehospital setting. The aim of this work was to determine the ability of prehospital cortisol levels to correlate to pain. Cortisol levels were compared with those of the numerical rating scale (NRS).
Methods
This is a prospective observational study looking at adult patients with acute disease managed by Emergency Medical Services (EMS) and transferred to the emergency department of two tertiary care hospitals. Epidemiological variables, vital signs, and prehospital blood analysis data were collected. A total of 1516 patients were included, the median age was 67 years (IQR: 51–79; range: 18–103) with 42.7% of females. The primary outcome was pain evaluation by NRS, which was categorized as pain-free (0 points), mild (1–3), moderate (4–6), or severe (≥7). Analysis of variance, correlation, and classification capacity in the form area under the curve of the receiver operating characteristic (AUC) curve were used to prospectively evaluate the association of cortisol with NRS.
Results
The median NRS and cortisol level are 1 point (IQR: 0–4) and 282 nmol/L (IQR: 143–433). There are 584 pain-free patients (38.5%), 525 mild (34.6%), 244 moderate (16.1%), and 163 severe pain (10.8%). Cortisol levels in each NRS category result in p < 0.001. The correlation coefficient between the cortisol level and NRS is 0.87 (p < 0.001). The AUC of cortisol to classify patients into each NRS category is 0.882 (95% CI: 0.853–0.910), 0.496 (95% CI: 0.446–0.545), 0.837 (95% CI: 0.803–0.872), and 0.981 (95% CI: 0.970–0.991) for the pain-free, mild, moderate, and severe categories, respectively.
Conclusions
Cortisol levels show similar pain evaluation as NRS, with high-correlation for NRS pain categories, except for mild-pain. Therefore, cortisol evaluation via the EMS could provide information regarding pain status.
metadata
López-Izquierdo, Raúl; Ingelmo-Astorga, Elisa A.; del Pozo Vegas, Carlos; Gracia Villar, Santos; Dzul López, Luis Alonso; Aparicio Obregón, Silvia; Calderón Iglesias, Rubén; Sanz-García, Ancor and Martín-Rodríguez, Francisco
mail
UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, santos.gracia@uneatlantico.es, luis.dzul@uneatlantico.es, silvia.aparicio@uneatlantico.es, ruben.calderon@uneatlantico.es, UNSPECIFIED, UNSPECIFIED
(2025)
Association between blood cortisol levels and numerical rating scale in prehospital pain assessment.
Communications Medicine, 5 (1).
ISSN 2730-664X
Article
Subjects > Biomedicine
Europe University of Atlantic > Research > Scientific Production
Fundación Universitaria Internacional de Colombia > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Articles and Books
Universidad Internacional do Cuanza > Research > Scientific Production
University of La Romana > Research > Scientific Production
Open
English
Background
Nowadays, there is no correlation between levels of cortisol and pain in the prehospital setting. The aim of this work was to determine the ability of prehospital cortisol levels to correlate to pain. Cortisol levels were compared with those of the numerical rating scale (NRS).
Methods
This is a prospective observational study looking at adult patients with acute disease managed by Emergency Medical Services (EMS) and transferred to the emergency department of two tertiary care hospitals. Epidemiological variables, vital signs, and prehospital blood analysis data were collected. A total of 1516 patients were included, the median age was 67 years (IQR: 51–79; range: 18–103) with 42.7% of females. The primary outcome was pain evaluation by NRS, which was categorized as pain-free (0 points), mild (1–3), moderate (4–6), or severe (≥7). Analysis of variance, correlation, and classification capacity in the form area under the curve of the receiver operating characteristic (AUC) curve were used to prospectively evaluate the association of cortisol with NRS.
Results
The median NRS and cortisol level are 1 point (IQR: 0–4) and 282 nmol/L (IQR: 143–433). There are 584 pain-free patients (38.5%), 525 mild (34.6%), 244 moderate (16.1%), and 163 severe pain (10.8%). Cortisol levels in each NRS category result in p < 0.001. The correlation coefficient between the cortisol level and NRS is 0.87 (p < 0.001). The AUC of cortisol to classify patients into each NRS category is 0.882 (95% CI: 0.853–0.910), 0.496 (95% CI: 0.446–0.545), 0.837 (95% CI: 0.803–0.872), and 0.981 (95% CI: 0.970–0.991) for the pain-free, mild, moderate, and severe categories, respectively.
Conclusions
Cortisol levels show similar pain evaluation as NRS, with high-correlation for NRS pain categories, except for mild-pain. Therefore, cortisol evaluation via the EMS could provide information regarding pain status.
metadata
López-Izquierdo, Raúl; Ingelmo-Astorga, Elisa A.; del Pozo Vegas, Carlos; Gracia Villar, Santos; Dzul López, Luis Alonso; Aparicio Obregón, Silvia; Calderón Iglesias, Rubén; Sanz-García, Ancor and Martín-Rodríguez, Francisco
mail
UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, santos.gracia@uneatlantico.es, luis.dzul@uneatlantico.es, silvia.aparicio@uneatlantico.es, ruben.calderon@uneatlantico.es, UNSPECIFIED, UNSPECIFIED
(2025)
Association between blood cortisol levels and numerical rating scale in prehospital pain assessment.
Communications Medicine, 5 (1).
ISSN 2730-664X
Article
Subjects > Biomedicine
Europe University of Atlantic > Research > Scientific Production
Fundación Universitaria Internacional de Colombia > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Articles and Books
Universidad Internacional do Cuanza > Research > Scientific Production
University of La Romana > Research > Scientific Production
Open
English
The aim of the present work was to determine the correlation between the State-Trait Anxiety Inventory (STAI) score and pupillary diameter and whether this correlation exists to develop a predictive model of anxiety with the pupillary diameter of students exposed to high-fidelity clinical simulation. This was a randomized, blinded, simulation-based clinical trial. The study was conducted at the Advanced Clinical Simulation Center, Faculty of Medicine, Valladolid University (Spain), from February 1 to April 15, 2023, and involved volunteer sixth-year undergraduate medical students. The STAI score, vital signs (oxygen saturation, perfusion index, blood pressure, heart rate, and temperature), and pupillary response were assessed. The primary outcomes were the delta (pre/postsimulation) of the state STAI and the delta of the pupillary diameter. Sixty-one sixth-year students fulfilled the inclusion criteria. There was no difference regarding the clinical scenario. There was a statistically significant correlation between the state STAI score and pupillary diameter. The predictive model had an AUC of 0.876, with the delta diameter of the pupillary being the only statistically significant variable for anxiety prediction. Our results showed that both the pupillary response and the STAI score allowed the identification of students with disabling anxiety. These results could pave the way for appropriate protocol development that allows for personalized tutoring of students with elevated anxiety levels.
metadata
Martín-Rodríguez, Francisco; Martín-Sánchez, Rafael; del Pozo Vegas, Carlos; Lopez-Izquierdo, Raúl; Martín-Conty, José Luis; Silva Alvarado, Eduardo René; Gracia Villar, Santos; Dzul López, Luis Alonso; Aparicio Obregón, Silvia; Calderón Iglesias, Rubén; Sanz-García, Ancor and Castro Villamor, Miguel Ángel
mail
UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, eduardo.silva@funiber.org, santos.gracia@uneatlantico.es, luis.dzul@uneatlantico.es, silvia.aparicio@uneatlantico.es, ruben.calderon@uneatlantico.es, UNSPECIFIED, UNSPECIFIED
(2025)
Pupilometer efficacy in monitoring anxiety in undergraduate medical students during high-fidelity clinical simulation.
Scientific Reports, 15 (1).
ISSN 2045-2322
Article
Subjects > Biomedicine
Subjects > Engineering
Europe University of Atlantic > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Articles and Books
Universidad Internacional do Cuanza > Research > Scientific Production
University of La Romana > Research > Scientific Production
Open
English
Virtual histopathology is an emerging technology in medical imaging that utilizes advanced computational methods to analyze tissue images for more precise disease diagnosis. Traditionally, histopathology relies on manual techniques and expertise, often resulting in time-consuming processes and variability in diagnoses. Virtual histopathology offers a more consistent, and automated approach, employing techniques like machine learning, deep learning, and image processing to simulate staining and enhance tissue analysis. This review explores the strengths, limitations, and clinical applications of these methods, highlighting recent advancements in virtual histopathological approaches. In addition, important areas are identified for future research to improve diagnostic accuracy and efficiency in clinical settings.
metadata
Imran, Muhammad Talha; Shafi, Imran; Ahmad, Jamil; Butt, Muhammad Fasih Uddin; Gracia Villar, Santos; García Villena, Eduardo; Khurshaid, Tahir and Ashraf, Imran
mail
UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, santos.gracia@uneatlantico.es, eduardo.garcia@uneatlantico.es, UNSPECIFIED, UNSPECIFIED
(2024)
Virtual histopathology methods in medical imaging - a systematic review.
BMC Medical Imaging, 24 (1).
ISSN 1471-2342
Article
Subjects > Biomedicine
Europe University of Atlantic > Research > Scientific Production
Fundación Universitaria Internacional de Colombia > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Articles and Books
Universidad Internacional do Cuanza > Research > Scientific Production
University of La Romana > Research > Scientific Production
Open
English
Emergency medical services (EMSs) face critical situations that require patient risk classification based on analytical and vital signs. We aimed to establish clustering-derived phenotypes based on prehospital analytical and vital signs that allow risk stratification. This was a prospective, multicenter, EMS-delivered, ambulance-based cohort study considering six advanced life support units, 38 basic life support units, and four tertiary hospitals in Spain. Adults with unselected acute diseases managed by the EMS and evacuated with discharge priority to emergency departments were considered between January 1, 2020, and June 30, 2023. Prehospital point-of-care testing and on-scene vital signs were used for the unsupervised machine learning method (clustering) to determine the phenotypes. Then phenotypes were compared with the primary outcome (cumulative mortality (all-cause) at 2, 7, and 30 days). A total of 7909 patients were included. The median (IQR) age was 64 (51–80) years, 41% were women, and 26% were living in rural areas. Three clusters were identified: alpha 16.2% (1281 patients), beta 28.8% (2279), and gamma 55% (4349). The mortality rates for alpha, beta and gamma at 2 days were 18.6%, 4.1%, and 0.8%, respectively; at 7 days, were 24.7%, 6.2%, and 1.7%; and at 30 days, were 33%, 10.2%, and 3.2%, respectively. Based on standard vital signs and blood test biomarkers in the prehospital scenario, three clusters were identified: alpha (high-risk), beta and gamma (medium- and low-risk, respectively). This permits the EMS system to quickly identify patients who are potentially compromised and to proactively implement the necessary interventions.
metadata
López-Izquierdo, Raúl; del Pozo Vegas, Carlos; Sanz-García, Ancor; Mayo Íscar, Agustín; Castro Villamor, Miguel A.; Silva Alvarado, Eduardo René; Gracia Villar, Santos; Dzul López, Luis Alonso; Aparicio Obregón, Silvia; Calderón Iglesias, Rubén; Soriano, Joan B. and Martín-Rodríguez, Francisco
mail
UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, eduardo.silva@funiber.org, santos.gracia@uneatlantico.es, luis.dzul@uneatlantico.es, silvia.aparicio@uneatlantico.es, ruben.calderon@uneatlantico.es, UNSPECIFIED, UNSPECIFIED
(2024)
Clinical phenotypes and short-term outcomes based on prehospital point-of-care testing and on-scene vital signs.
npj Digital Medicine, 7 (1).
ISSN 2398-6352
Article
Subjects > Biomedicine
Europe University of Atlantic > Research > Scientific Production
Fundación Universitaria Internacional de Colombia > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Articles and Books
Universidad Internacional do Cuanza > Research > Scientific Production
University of La Romana > Research > Scientific Production
Open
English
Emergency medical services (EMSs) face critical situations that require patient risk classification based on analytical and vital signs. We aimed to establish clustering-derived phenotypes based on prehospital analytical and vital signs that allow risk stratification. This was a prospective, multicenter, EMS-delivered, ambulance-based cohort study considering six advanced life support units, 38 basic life support units, and four tertiary hospitals in Spain. Adults with unselected acute diseases managed by the EMS and evacuated with discharge priority to emergency departments were considered between January 1, 2020, and June 30, 2023. Prehospital point-of-care testing and on-scene vital signs were used for the unsupervised machine learning method (clustering) to determine the phenotypes. Then phenotypes were compared with the primary outcome (cumulative mortality (all-cause) at 2, 7, and 30 days). A total of 7909 patients were included. The median (IQR) age was 64 (51–80) years, 41% were women, and 26% were living in rural areas. Three clusters were identified: alpha 16.2% (1281 patients), beta 28.8% (2279), and gamma 55% (4349). The mortality rates for alpha, beta and gamma at 2 days were 18.6%, 4.1%, and 0.8%, respectively; at 7 days, were 24.7%, 6.2%, and 1.7%; and at 30 days, were 33%, 10.2%, and 3.2%, respectively. Based on standard vital signs and blood test biomarkers in the prehospital scenario, three clusters were identified: alpha (high-risk), beta and gamma (medium- and low-risk, respectively). This permits the EMS system to quickly identify patients who are potentially compromised and to proactively implement the necessary interventions.
metadata
López-Izquierdo, Raúl; del Pozo Vegas, Carlos; Sanz-García, Ancor; Mayo Íscar, Agustín; Castro Villamor, Miguel A.; Silva Alvarado, Eduardo René; Gracia Villar, Santos; Dzul López, Luis Alonso; Aparicio Obregón, Silvia; Calderón Iglesias, Rubén; Soriano, Joan B. and Martín-Rodríguez, Francisco
mail
UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, eduardo.silva@funiber.org, santos.gracia@uneatlantico.es, luis.dzul@uneatlantico.es, silvia.aparicio@uneatlantico.es, ruben.calderon@uneatlantico.es, UNSPECIFIED, UNSPECIFIED
(2024)
Clinical phenotypes and short-term outcomes based on prehospital point-of-care testing and on-scene vital signs.
npj Digital Medicine, 7 (1).
ISSN 2398-6352
Article
Subjects > Biomedicine
Subjects > Engineering
Europe University of Atlantic > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Articles and Books
Universidad Internacional do Cuanza > Research > Scientific Production
Open
English
A novel approach is presented in this study for the classification of lower limb disorders, with a specific emphasis on the knee, hip, and ankle. The research employs gait analysis and the extraction of PoseNet features from video data in order to effectively identify and categorize these disorders. The PoseNet algorithm facilitates the extraction of key body joint movements and positions from videos in a non-invasive and user-friendly manner, thereby offering a comprehensive representation of lower limb movements. The features that are extracted are subsequently standardized and employed as inputs for a range of machine learning algorithms, such as Random Forest, Extra Tree Classifier, Multilayer Perceptron, Artificial Neural Networks, and Convolutional Neural Networks. The models undergo training and testing processes using a dataset consisting of 174 real patients and normal individuals collected at the Tehsil Headquarter Hospital Sadiq Abad. The evaluation of their performance is conducted through the utilization of K-fold cross-validation. The findings exhibit a notable level of accuracy and precision in the classification of various lower limb disorders. Notably, the Artificial Neural Networks model achieves the highest accuracy rate of 98.84%. The proposed methodology exhibits potential in enhancing the diagnosis and treatment planning of lower limb disorders. It presents a non-invasive and efficient method of analyzing gait patterns and identifying particular conditions.
metadata
Siddiqui, Hafeez Ur Rehman; Saleem, Adil Ali; Raza, Muhammad Amjad; Gracia Villar, Santos; Dzul Lopez, Luis; Diez, Isabel de la Torre; Rustam, Furqan and Dudley, Sandra
mail
UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, santos.gracia@uneatlantico.es, luis.dzul@unini.edu.mx, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED
(2023)
Empowering Lower Limb Disorder Identification through PoseNet and Artificial Intelligence.
Diagnostics, 13 (18).
p. 2881.
ISSN 2075-4418
Article
Subjects > Engineering
Europe University of Atlantic > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Articles and Books
Universidad Internacional do Cuanza > Research > Scientific Production
Open
English
Agriculture is a critical domain, where technology can have a significant impact on increasing yields, improving crop quality, and reducing environmental impact. The use of renewable energy sources such as solar power in agriculture has gained momentum in recent years due to the potential to reduce the carbon footprint of farming operations. In addition to providing a source of clean energy, solar tracking systems can also be used for remote weather monitoring in the agricultural field. The ability to collect real-time data on weather parameters such as temperature, humidity, and rainfall can help farmers make informed decisions on irrigation, pest control, and other crop management practices. The main idea of this study is to present a system that can improve the efficiency of solar panels to provide constant power to the sensor in the agricultural field and transfer real-time data to the app. This research presents a mechanism to improve the arrangement of a photovoltaic (PV) array with solar power and to produce maximum energy. The proposed system changes its direction in two axes (azimuth and elevation) by detecting the difference between the position of the sun and the panel to track the sun using a light-dependent resistor. A testbed with a hardware experimental setup is designed to test the system’s capability to track according to the position of the sun effectively. In the end, real-time data are displayed using the Android app, and the weather data are transferred to the app using a GSM/WiFi module. This research improves the existing system, and results showed that the relative increase in power generation was up to 52%. Using intelligent artificial intelligence techniques with the QoS algorithm, the quality of service produced by the existing system is improved.
metadata
Kanwal, Tabassum; Rehman, Saif Ur; Ali, Tariq; Mahmood, Khalid; Gracia Villar, Santos; Dzul Lopez, Luis and Ashraf, Imran
mail
UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, santos.gracia@uneatlantico.es, luis.dzul@unini.edu.mx, UNSPECIFIED
(2023)
An Intelligent Dual-Axis Solar Tracking System for Remote Weather Monitoring in the Agricultural Field.
Agriculture, 13 (8).
p. 1600.
ISSN 2077-0472
Article
Subjects > Biomedicine
Subjects > Engineering
Europe University of Atlantic > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Articles and Books
Universidad Internacional do Cuanza > Research > Scientific Production
Open
English
In the last decade, artificial intelligence (AI) and AI-mediated technologies have undergone rapid evolution in healthcare and medicine, from apps to computer software able to analyze medical images, robotic surgery and advanced data storage system. The main aim of the present commentary is to briefly describe the evolution of AI and its applications in healthcare, particularly in nutrition and clinical biochemistry. Indeed, AI is revealing itself to be an important tool in clinical nutrition by using telematic means to self-monitor various health metrics, including blood glucose levels, body weight, heart rate, fat percentage, blood pressure, activity tracking and calorie intake trackers. In particular, the application of the most common digital technologies used in the field of nutrition as well as the employment of AI in the management of diabetes and obesity, two of the most common nutrition-related pathologies worldwide, will be presented.
metadata
Salinari, Alessia; Machì, Michele; Armas Diaz, Yasmany; Cianciosi, Danila; Qi, Zexiu; Yang, Bei; Ferreiro Cotorruelo, Maria Soledad; Gracia Villar, Santos; Dzul López, Luis Alonso; Battino, Maurizio and Giampieri, Francesca
mail
UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, santos.gracia@uneatlantico.es, luis.dzul@uneatlantico.es, maurizio.battino@uneatlantico.es, francesca.giampieri@uneatlantico.es
(2023)
The Application of Digital Technologies and Artificial Intelligence in Healthcare: An Overview on Nutrition Assessment.
Diseases, 11 (3).
p. 97.
ISSN 2079-9721
Article
Subjects > Social Sciences
Europe University of Atlantic > Research > Scientific Production
Fundación Universitaria Internacional de Colombia > Research > Scientific Production
Ibero-american International University > Research > Scientific Production
Ibero-american International University > Research > Articles and Books
Universidad Internacional do Cuanza > Research > Scientific Production
Open
English
This article proposes a discussion on the form of coexistence of local Development Agencies in Uruguay, with local governments in the face of the new scenarios marked by the decentralization process, initiated in the country with the Constitutional Reform of 1996 and culminating in February 2009, with the Law of Political Decentralization and Citizen Participation. The discussion applies in particular to the local development agency of the city of Rivera (ADR), located in the northeast of the country. A descriptive, mixed, bibliographic, documentary investigation was carried out with primary data collection to internal and external references to ADR. The results show that the coexistence of both institutions has been difficult, without defining clear roles. Promoting dialogue to define the role of each seems to be the great challenge facing the sustainability of the agency
metadata
Garat de Marin, Mirtha Silvana; Soriano Flores, Emmanuel; Rodríguez Velasco, Carmen Lilí; Silva Alvarado, Eduardo; Calderón Iglesias, Rubén; Álvarez, Roberto Marcelo and Gracia Villar, Santos
mail
silvana.marin@uneatlantico.es, emmanuel.soriano@uneatlantico.es, carmen.rodriguez@uneatlantico.es, UNSPECIFIED, ruben.calderon@uneatlantico.es, roberto.alvarez@uneatlantico.es, santos.gracia@uneatlantico.es
(2022)
Development Agencies and Local Governments—Coexistence within the Same Territory.
Social Sciences, 11 (9).
p. 398.
ISSN 2076-0760
<a href="/27825/1/s41598-026-39196-x_reference.pdf" class="ep_document_link"><img class="ep_doc_icon" alt="[img]" src="/style/images/fileicons/text.png" border="0"/></a>
en
open
Histopathological evaluation is necessary for the diagnosis and grading of prostate cancer, which is still one of the most common cancers in men globally. Traditional evaluation is time-consuming, prone to inter-observer variability, and challenging to scale. The clinical usefulness of current AI systems is limited by the need for comprehensive pixel-level annotations. The objective of this research is to develop and evaluate a large-scale benchmarking study on a weakly supervised deep learning framework that minimizes the need for annotation and ensures interpretability for automated prostate cancer diagnosis and International Society of Urological Pathology (ISUP) grading using whole slide images (WSIs). This study rigorously tested six cutting-edge multiple instance learning (MIL) architectures (CLAM-MB, CLAM-SB, ILRA-MIL, AC-MIL, AMD-MIL, WiKG-MIL), three feature encoders (ResNet50, CTransPath, UNI2), and four patch extraction techniques (varying sizes and overlap) using the PANDA dataset (10,616 WSIs), yielding 72 experimental configurations. The methodology used distributed cloud computing to process over 31 million tissue patches, implementing advanced attention mechanisms to ensure clinical interpretability through Grad-CAM visualizations. The optimum configuration (UNI2 encoder with ILRA-MIL, 256 256 patches, 50% overlap) achieved 78.75% accuracy and 90.12% quadratic weighted kappa (QWK), outperforming traditional methods and approaching expert pathologist-level diagnostic capability. Overlapping smaller patches offered the best balance of spatial resolution and contextual information, while domain-specific foundation models performed noticeably better than generic encoders. This work is the first large-scale, comprehensive comparison of weekly supervised MIL methods for prostate cancer diagnosis and grading. The proposed approach has excellent clinical diagnostic performance, scalability, practical feasibility through cloud computing, and interpretability using visualization tools.
Naveed Anwer Butt mail , Dilawaiz Sarwat mail , Irene Delgado Noya mail irene.delgado@uneatlantico.es, Kilian Tutusaus mail kilian.tutusaus@uneatlantico.es, Nagwan Abdel Samee mail , Imran Ashraf mail ,
Butt
<a href="/27915/1/csbj.0023.pdf" class="ep_document_link"><img class="ep_doc_icon" alt="[img]" src="/style/images/fileicons/text.png" border="0"/></a>
en
open
This systematic literature review (SLR) investigates the integration of deep learning (DL), vision-language models(VLMs), and multi-agent systems in the analysis of pathology images and automated report generation. The rapidadvancement of whole-slide imaging (WSI) technologies has posed new challenges in pathology, especially due to thescale and complexity of the data. DL techniques in general and convolutional neural networks (CNNs) and transform-ers in particular have significantly enhanced image analysis tasks including segmentation, classification, and detection.However, these models often lack generalizability to generate coherent, clinically relevant text, thus necessitating theintegration of VLMs and large language models (LLMs). This review examines the effectiveness of VLMs and LLMsin bridging the gap between visual data and clinical text, focusing on their potential for automating the generationof pathology reports. Additionally, multi-agent systems, which leverage specialized artificial intelligence (AI) agentsto collaboratively perform diagnostic tasks, are explored for their contributions to improving diagnostic accuracy andscalability. Through a synthesis of recent studies, this review highlights the successes, challenges, and future direc-tions of these AI technologies in pathology diagnostics, offering a comprehensive foundation for the development ofintegrated, AI-driven diagnostic workflows.
Usama Ali mail , Imran Shafi mail , Jamil Ahmad mail , Arlette Zárate Cáceres mail , Thania Chio Montero mail , Hafiz Muhammad Raza ur Rehman mail , Imran Ashraf mail ,
Ali
<a href="/27970/1/s11357-026-02188-w.pdf" class="ep_document_link"><img class="ep_doc_icon" alt="[img]" src="/style/images/fileicons/text.png" border="0"/></a>
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Fish consumption and cognitive function in aging: a systematic review of observational studies
Epidemiological studies consistently link higher fish intake with slower rates of cognitive decline and lower dementia incidence. The aim of the present study was to systematically review existing observational studies investigating the association between fish consumption and cognitive function in older adults. A total of 25 studies (8 cross-sectional and 17 prospective including mainly healthy older adults, age range of participants ranging from 18 to 30 years at baseline in prospective studies to 65 to 91 years, representing the upper limit of the age spectrum) were reviewed. Cognitive functions currently investigated in most published studies included various domains, such as global cognition, memory (episodic, working), executive function (planning, inhibition, flexibility), attention and processing speed. Existing studies greatly vary in terms of design (cross-sectional and prospective), geographical area, number of participants involved, and tools used to assess the outcomes of interest. The main findings across studies are not univocal, with some studies reporting stronger evidence of association between fish consumption and various cognitive domains, while others addressed rather null findings. The most consistently responsive domains were processing speed, executive functioning, semantic memory, and global cognitive ability among individuals consuming fish at least weekly, which are highly relevant to both neurodegenerative and vascular forms of cognitive impairment. Positive associations were also observed for verbal memory and general memory, though these were less uniform and often attenuated after multivariable adjustment. In contrast, associations with reaction time, verbal-numerical reasoning, and broad composite scores were inconsistent, and several fully adjusted models showed null results. In conclusion, the evidence suggests that regular fish intake (typically ≥1–2 servings per week) is linked to preserved cognitive performance, although some inconsistent findings require further investigations.
Justyna Godos mail , Giuseppe Caruso mail , Agnieszka Micek mail , Alberto Dolci mail , Carmen Lilí Rodríguez Velasco mail carmen.rodriguez@uneatlantico.es, Evelyn Frias-Toral mail , Jason Di Giorgio mail , Nicola Veronese mail , Andrea Lehoczki mail , Mario Siervo mail , Zoltan Ungvari mail , Giuseppe Grosso mail ,
Godos
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A scalable and secure federated learning authentication scheme for IoT
Secure and scalable authentication remains a fundamental challenge in Internet of Things (IoT) networks due to constrained device resources, dynamic topology, and the absence of centralized trust infrastructures. Conventional password-based and certificate-driven authentication schemes incur high computation, storage, and communication overhead, limiting their suitability for large-scale deployments. To address these limitations, this paper proposes ScLBS, a federated learning (FL)–based self-certified authentication scheme for distributed and sustainable IoT environments. ScLBS integrates self-certified public key cryptography with FL-driven trust adaptation, enabling decentralized public key derivation without reliance on third-party certificate authorities or exposure of private credentials. A zero-knowledge mechanism combined with location-aware authentication strengthens resistance to impersonation, Sybil, and replay attacks. Hierarchical key management supported by a -tree enables efficient group rekeying and preserves forward and backward secrecy under dynamic membership. Formal security verification is conducted under the Dolev–Yao adversary model using ProVerif, confirming secrecy of private and session keys (SKs) and correctness of authentication. Extensive NS-3 simulations and ablation analysis demonstrate that ScLBS achieves lower authentication delay, reduced message overhead, improved network utilization, and decreased energy consumption compared to representative IoT authentication schemes, while maintaining bounded FL overhead. These results indicate that ScLBS provides a balanced trade-off between security strength, scalability, and resource efficiency for constrained IoT networks.
Premkumar Chithaluru mail , B. Veera Jyothi mail , Fahd S. Alharithi mail , Wojciech Ksiazek mail , M. Ramchander mail , Aman Singh mail aman.singh@uneatlantico.es, Ravi Kumar Rachavaram mail ,
Chithaluru
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Human Activity Recognition in Domestic Settings Based on Optical Techniques and Ensemble Models
Human activity recognition (HAR) is essential in many applications, such as smart homes, assisted living, healthcare monitoring, rehabilitation, physiotherapy, and geriatric care. Conventional methods of HAR use wearable sensors, e.g., acceleration sensors and gyroscopes. However, they are limited by issues such as sensitivity to position, user inconvenience, and potential health risks with long-term use. Optical camera systems that are vision-based provide an alternative that is not intrusive; however, they are susceptible to variations in lighting, intrusions, and privacy issues. The paper uses an optical method of recognizing human domestic activities based on pose estimation and deep learning ensemble models. The skeletal keypoint features proposed in the current methodology are extracted from video data using PoseNet to generate a privacy-preserving representation that captures key motion dynamics without being sensitive to changes in appearance. A total of 30 subjects (15 male and 15 female) were sampled across 2734 activity samples, including nine daily domestic activities. There were six deep learning architectures, namely, the Transformer (Transformer), Long Short-Term Memory (LSTM), Gated Recurrent Unit (GRU), Multilayer Perceptron (MLP), One-Dimensional Convolutional Neural Network (1D CNN), and a hybrid Convolutional Neural Network–Long Short-Term Memory (CNN–LSTM) architecture. The results on the hold-out test set show that the CNN–LSTM architecture achieves an accuracy of 98.78% within our experimental setting. Leave-One-Subject-Out cross-validation further confirms robust generalization across unseen individuals, with CNN–LSTM achieving a mean accuracy of 97.21% ± 1.84% across 30 subjects. The results demonstrate that vision-based pose estimation with deep learning is a useful, precise, and non-intrusive approach to HAR in smart healthcare and home automation systems.
Muhammad Amjad Raza mail , Nasir Mehmood mail , Hafeez Ur Rehman Siddiqui mail , Adil Ali Saleem mail , Roberto Marcelo Álvarez mail roberto.alvarez@uneatlantico.es, Yini Airet Miró Vera mail yini.miro@uneatlantico.es, Isabel de la Torre Díez mail ,
Raza
